{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:07:27Z","timestamp":1791248847245,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,11,20]],"date-time":"2013-11-20T00:00:00Z","timestamp":1384905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>Mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>) represents the most common epidermotropic cutaneous T\u2010cell lymphoma (<jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>), and tumor cells typically express a mature T\u2010helper memory phenotype. A minority of <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> patients display an unusual phenotype, which may be either <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content>(\u2212)\/<jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content>(+) or double negative. Herein, we report a case of biopsy\u2010proven <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> in a 31\u2010year\u2010old woman who presented with infiltrated plaques involving photoprotected areas of the skin. Immunohistochemical study combined with confocal microscopy revealed co\u2010expression of <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content> in a subset of atypical T lymphocytes. To our knowledge, this is the second report of a <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content> dual\u2010positive <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cup.12248","type":"journal-article","created":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T14:12:42Z","timestamp":1382019162000},"page":"58-62","source":"Crossref","is-referenced-by-count":25,"title":["Double\u2010positive <scp>CD4<\/scp>\/<scp>CD8<\/scp> mycosis fungoides: a rarely reported immunohistochemical profile"],"prefix":"10.1111","volume":"41","author":[{"given":"Emilie","family":"Tournier","sequence":"first","affiliation":[{"name":"Laboratoire d'Anatomie Pathologique CHU Purpan Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Laurent","sequence":"additional","affiliation":[{"name":"Laboratoire d'Anatomie Pathologique CHU Purpan Toulouse France"},{"name":"Universit\u00e9 Paul\u2010Sabatier Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Larrey Hospital, CHU de Toulouse Toulouse Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Larrey Hospital, CHU de Toulouse Toulouse Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Viraben","sequence":"additional","affiliation":[{"name":"Department of Dermatology Larrey Hospital, CHU de Toulouse Toulouse Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Brousset","sequence":"additional","affiliation":[{"name":"Laboratoire d'Anatomie Pathologique CHU Purpan Toulouse France"},{"name":"Universit\u00e9 Paul\u2010Sabatier Toulouse France"},{"name":"INSERM U1037 CRCT Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Lamant","sequence":"additional","affiliation":[{"name":"Laboratoire d'Anatomie Pathologique CHU Purpan Toulouse France"},{"name":"Universit\u00e9 Paul\u2010Sabatier Toulouse France"},{"name":"INSERM U1037 CRCT Toulouse 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