{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T06:07:32Z","timestamp":1783750052886,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T00:00:00Z","timestamp":1394150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Cutaneous lymphatic malformations represent a group of heterogeneous diseases. In clinical practice, some cases of cutaneous lymphatic malformation have been found to differ from the well\u2010characterized entities, and are difficult to classify.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the clinical, histopathological and immunohistochemical characteristics of six cases of lymphatic malformation characterized by swelling of the digits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Six patients with swelling of the digits were included in this study. Histopathological examination and immunohistochemical staining of <jats:styled-content style=\"fixed-case\">CD31<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">D2<\/jats:styled-content>\u201040, Prox1, Wilms tumor 1 (<jats:styled-content style=\"fixed-case\">WT<\/jats:styled-content>\u20101) and human herpesvirus\u20108 (<jats:styled-content style=\"fixed-case\">HHV<\/jats:styled-content>\u20108) were performed for all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All cases were congenital lesions and presented as swelling of single or multiple digits. Histopathologically, the lesions showed proliferation of small\u2010to\u2010medium\u2010sized vessels in the dermis and subcutaneous tissue. These abnormal vessels were positive for <jats:styled-content style=\"fixed-case\">CD31<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">D2<\/jats:styled-content>\u201040 and Prox1, and negative for <jats:styled-content style=\"fixed-case\">WT<\/jats:styled-content>\u20101 and <jats:styled-content style=\"fixed-case\">HHV<\/jats:styled-content>\u20108.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The six cases reported herein represent a specific cutaneous lymphatic malformation different from previously reported entities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12312","type":"journal-article","created":{"date-parts":[[2014,2,12]],"date-time":"2014-02-12T11:48:42Z","timestamp":1392205722000},"page":"451-456","source":"Crossref","is-referenced-by-count":3,"title":["Cutaneous lymphatic malformation characterized by swelling of digits: a report of six cases"],"prefix":"10.1111","volume":"41","author":[{"given":"Lei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwen","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1385\/1592593607"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1976.tb05134.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640010026002"},{"key":"e_1_2_5_5_1","first-page":"733","volume-title":"Enzinger and Weiss's soft tissue tumours","author":"Weiss SW","year":"2008"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.05.019"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.05.025"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12216"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12143"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-1010fje"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2350\/08-05-0471.1"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318236c312"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182092527"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.12.017"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199304000-00002"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199502000-00001"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550310002693"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.01892"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000200020"},{"key":"e_1_2_5_20_1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1001\/archderm.1970.04000040094019","article-title":"Cutaneous lymphangiomas with dyschondroplasia (Maffucci's syndrome). 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