{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T16:16:27Z","timestamp":1772640987684,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T00:00:00Z","timestamp":1398729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>A 71\u2010year\u2010old woman presented with five scalp nodules that were clinically suspicious for pilar cysts. Histopathologic examination showed a proliferation of mitotically active pleomorphic spindle cells arranged into intersecting fascicles in the dermis and subcutis. Tumor cells displayed deeply eosinophilic cytoplasm and expressed desmin but were negative for <jats:styled-content style=\"fixed-case\">S100<\/jats:styled-content> protein by immunohistochemistry. Before 10\u2009years, the patient was diagnosed with high\u2010grade retroperitoneal leiomyosarcoma and underwent resection with intraoperative radiation. Metastatic disease involving the lungs, liver and soft tissue developed, requiring treatment with resections, radiation and chemotherapy. Owing to the presentation of multiple scalp nodules with microscopic features of leiomyosarcoma in conjunction with the clinical history of retroperitoneal leiomyosarcoma, a diagnosis of metastatic leiomyosarcoma was made. Scalp metastasis from retroperitoneal leiomyosarcoma is extremely rare and portends a poor prognosis. To our knowledge, only two other cases have been reported in the English literature, and a further search discovered only nine additional cases of scalp metastasis from soft tissue leiomyosarcoma of any non\u2010gynecologic anatomic site. This case highlights the striking microscopic similarity between primary cutaneous and metastatic leiomyosarcoma and illustrates the necessity of adequate clinical information and an appropriate index of suspicion in excluding the possibility of cutaneous metastases of leiomyosarcoma from somatic soft tissue.<\/jats:p>","DOI":"10.1111\/cup.12329","type":"journal-article","created":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T19:30:27Z","timestamp":1394825427000},"page":"680-685","source":"Crossref","is-referenced-by-count":7,"title":["Cutaneous scalp metastases from retroperitoneal leiomyosarcoma: a case report"],"prefix":"10.1111","volume":"41","author":[{"given":"Rebekah G.","family":"Baltz","sequence":"first","affiliation":[{"name":"College of Medicine University of Arkansas for Medical Sciences  Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer R.","family":"Kaley","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Arkansas for Medical Sciences  Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl A.","family":"Hull","sequence":"additional","affiliation":[{"name":"Hull Dermatology, PA  Rogers AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerad M.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Arkansas for Medical Sciences  Little Rock AR USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,29]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33127.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-7-45"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90231-7"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/631010"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-7-85"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26590"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2001.01254-4.x"},{"key":"e_1_2_4_9_1","first-page":"1","article-title":"Leiomyosarcoma of the bone and soft tissue: a review","volume":"4","author":"Weaver MJ","year":"2007","journal-title":"Electron Update Sarcoma Newsl"},{"key":"e_1_2_4_10_1","first-page":"307","article-title":"Cutaneous and subcutaneous leiomyosarcoma. 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