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However, a number of well\u2010recognized and rare types of <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content>, including mycosis fungoides, can present in isolated fashion. These solitary lesions often run a relatively indolent clinical course but often pose diagnostic difficulties. We review histopathologically challenging solitary cutaneous T\u2010cell lymphomas, including criteria for diagnosis, clinical course and prognosis, particularly for primary cutaneous <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content>+ small\/medium pleomorphic lymphoma and indolent <jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content>+ lymphoid proliferation of acral sites. In addition, we suggest an algorithm and nomenclature to aid in the diagnosis of such problematic lesions.<\/jats:p>","DOI":"10.1111\/cup.12353","type":"journal-article","created":{"date-parts":[[2014,3,25]],"date-time":"2014-03-25T14:30:56Z","timestamp":1395757856000},"page":"703-714","source":"Crossref","is-referenced-by-count":24,"title":["A review of the solitary cutaneous T\u2010cell lymphomas"],"prefix":"10.1111","volume":"41","author":[{"given":"Mina S.","family":"Ally","sequence":"first","affiliation":[{"name":"Department of Dermatology Stanford University School of Medicine  Redwood City CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alistair","family":"Robson","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology St. Thomas' Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.07.009"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.02.039"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318068b527"},{"key":"e_1_2_10_6_1","first-page":"354","article-title":"EORTC classification for primary cutaneous lymphomas: a proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer","volume":"90","author":"Willemze R","year":"1997","journal-title":"Blood"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.03080.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000018232"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2012.01965.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000247579"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)01559-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182036ce7"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1994.tb03415.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199912000-00003"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70008-6"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90140-3"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000051542"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00218-1"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00553-1"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335570"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2010.06.003"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.27.7665"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.138.2.191"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2008.46"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181731dfc"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.057"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1309\/MTTM86UT1XFQL7RV"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01566.x"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.01.020"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08761.x"},{"key":"e_1_2_10_31_1","first-page":"446","article-title":"Unilesional mycosis fungoides successfully treated with imiquimod","volume":"16","author":"Ardigo M","year":"2006","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690150089018"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10728.x"},{"key":"e_1_2_10_34_1","unstructured":"Braun\u2010FalcoO MarghescuS WolffHH. 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