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The bone marrow biopsy contained atypical megakaryocytes that expressed <jats:styled-content style=\"fixed-case\">S100<\/jats:styled-content> in the cytoplasm. We discuss how such aberrant expression could be a source of some diagnostic problems in dermatopathology, including cutaneous melanoma, metastasis of melanoma in bone marrow and metastasis of melanoma in sentinel lymph nodes.<\/jats:p>","DOI":"10.1111\/cup.12426","type":"journal-article","created":{"date-parts":[[2014,11,5]],"date-time":"2014-11-05T11:40:01Z","timestamp":1415187601000},"page":"963-968","source":"Crossref","is-referenced-by-count":2,"title":["<scp>S100<\/scp> expression by atypical megakaryocytes: a previously unreported potential pitfall in dermatopathology"],"prefix":"10.1111","volume":"41","author":[{"given":"Angel","family":"Fernandez\u2010Flores","sequence":"first","affiliation":[{"name":"Department of Cellular Pathology Hospital El Bierzo  Ponferrada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco\u2010Javier","family":"D\u00edaz\u2010Galvez","sequence":"additional","affiliation":[{"name":"Department of Haematology Hospital El Bierzo  Ponferrada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/106689690301100404"},{"key":"e_1_2_5_3_1","first-page":"130","volume-title":"WHO classification of tumours of haematopoietic and lymphoid tissues","author":"Arber DA","year":"2008"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-2-38"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1995.tb03885.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1182\/blood.V94.4.1483","article-title":"Fulminant intravascular disseminating malignant melanoma mimicking acute leukemia","volume":"94","author":"Trefzer U","year":"1999","journal-title":"Blood"},{"key":"e_1_2_5_7_1","first-page":"164","article-title":"Extreme leucocytosis and splenomegaly in metastasised melanoma","volume":"62","author":"Wolff JF","year":"2004","journal-title":"Neth J Med"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-09-454546"},{"key":"e_1_2_5_9_1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/ajcp\/79.2.268","article-title":"Melanoma in marrow aspirates","volume":"79","author":"Savage RA","year":"1983","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19970501)79:9<1816::AID-CNCR26>3.0.CO;2-#"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1975.01360140040008"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820315)49:6<1106::AID-CNCR2820490607>3.0.CO;2-0"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000236"},{"key":"e_1_2_5_14_1","first-page":"101","article-title":"Fulminant metastatic melanoma complicated by a microangiopathic hemolytic anemia","volume":"11","author":"Bhagwati N","year":"1998","journal-title":"Hematopathol Mol Hematol"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950200117"},{"key":"e_1_2_5_16_1","first-page":"249","article-title":"Auto\u2010immune neutropenia occurring in association with malignant melanoma","volume":"10","author":"White JD","year":"2003","journal-title":"Oncol Rep"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12669"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1581"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0b013e32832dd2e8"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.124.3.329"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00502.x"},{"key":"e_1_2_5_22_1","first-page":"409","article-title":"Acute myelofibrosis \u2013 a leukemia of pluripotent stem cell. 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