{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T07:47:17Z","timestamp":1696405637719},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T00:00:00Z","timestamp":1432598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Bristol-Myers Squibb"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In 2009 the revised seventh staging system for melanoma recommended the use of mitotic count to separate stage T1a from T1b. However, careful scrutiny of cases may lead to an inadvertent selection effect, with consequent increased reporting of mitotic counts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated whether there is a significant increase in mitotic counts reported since 2009 for melanomas with a Breslow thickness of 1.0\u2009mm or less. We conducted a retrospective, case\u2010controlled study examining invasive melanoma cases at a large academic center. Mitotic counts were compared between pathology reports before 2009 (n\u2009=\u200961) and after 2009 (n\u2009=\u2009125), with a subset of slides re\u2010examined in a blinded fashion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Before the 2009 staging guidelines, 51% of cases had one or more mitosis reported compared to 38% after 2009 (p\u2009=\u20090.113). Blinded re\u2010counting did not yield a significant difference when compared with the original pathology reports in either group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was not a significant difference in the number of mitoses reported after the implementation of the new guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12517","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T12:15:20Z","timestamp":1430396120000},"page":"536-541","source":"Crossref","is-referenced-by-count":5,"title":["Impact of the 2009 <scp>AJCC<\/scp> staging guidelines for melanoma on the number of mitotic figures reported by dermatopathologists at one institution"],"prefix":"10.1111","volume":"42","author":[{"given":"Allison R.","family":"Larson","sequence":"first","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology, Brigham and Women's, Hospital Harvard Medical School  Boston MA USA"},{"name":"Department of Dermatology Boston Medical Center  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Rothschild","sequence":"additional","affiliation":[{"name":"Department of Dermatology Colorado Permanente Medical Group  Denver CO USA"},{"name":"Harvard Combined Dermatology Residency Program  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew C.","family":"Walls","sequence":"additional","affiliation":[{"name":"Harvard Combined Dermatology Residency Program  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott R.","family":"Granter","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology, Brigham and Women's, Hospital Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abrar A.","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Brigham and Women's Hospital Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George F.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology, Brigham and Women's, Hospital Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro C.","family":"Laga","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology, Brigham and Women's, Hospital Harvard Medical School  Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.4799"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.31.5812"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000161116"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.7734"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.07.016"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31829433b6"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181faab45"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00292-011-1465-8"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182604d96"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060992"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089161209800113"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310460"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2011.07714_suppl.x"}],"container-title":["Journal 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