{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T07:13:15Z","timestamp":1696317195089},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2015,12]]},"abstract":"ABSTRACT<\/jats:title>Background<\/jats:title>Cutaneous non\u2010mycosis fungoides non\u2010Sezary syndrome T\/NK<\/jats:styled-content> cell lymphomas (non\u2010MF<\/jats:styled-content>\/non\u2010SS CTCL<\/jats:styled-content>) are rare. In 2005, a consensus of the World Health Organization (WHO<\/jats:styled-content>) and European Organization for Research and Treatment of Cancer (EORTC<\/jats:styled-content>) classifications for primary cutaneous lymphomas was established. These guidelines were then adopted into the WHO<\/jats:styled-content> Classification of Tumours of Haematopoietic and Lymphoid Tissues, 2008. This study aims to assess the applicability of the WHO<\/jats:styled-content> 2008 classification in a retrospective series of CTCL<\/jats:styled-content> cases registered in a reference academic center in Brazil.<\/jats:p><\/jats:sec>Methods<\/jats:title>Twenty\u2010seven patients with non\u2010MF<\/jats:styled-content>\/non\u2010SS CTCL<\/jats:styled-content> were studied. Clinical, histopathological and immunophenotypical features based on an extensive panel of antibodies were applied to classify the cases according to the WHO<\/jats:styled-content>, 2008.<\/jats:p><\/jats:sec>Results<\/jats:title>Overall, diagnostic categories included eight (29.6%) cutaneous anaplastic large\u2010cell lymphoma, five (18.5%) lymphomatoid papulosis, six (22.2%) extranodal natural killer (NK<\/jats:styled-content>)\/T\u2010cell lymphoma, nasal type, five (18.5%) adult T\u2010cell leukemia\/lymphoma, one (3.7%) cutaneous CD8<\/jats:styled-content>\u2010positive aggressive epidermotropic cytotoxic T\u2010cell lymphoma and two (7.4%) of peripheral T\u2010cell lymphoma not otherwise specified (NOS<\/jats:styled-content>).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The WHO<\/jats:styled-content> classification (2008) was applicable to most cases of non\u2010MF<\/jats:styled-content>\/non\u2010SS CTCL<\/jats:styled-content>, while some cases remained unclassified and were considered NOS<\/jats:styled-content>\u2010peripheral T\u2010cell lymphoma. An unexpected high frequency of NK<\/jats:styled-content>\/T\u2010cell lymphoma nasal type was observed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12599","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T09:29:38Z","timestamp":1439458178000},"page":"965-973","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of the 2008 World Health Organization classification for non\u2010mycosis fungoides, non\u2010Sezary syndrome T\/NK<\/scp>\u2010cell lymphomas with primary cutaneous involvement"],"prefix":"10.1111","volume":"42","author":[{"given":"Daniel","family":"Chang","sequence":"first","affiliation":[{"name":"Pathology Laboratory Fleury Medicine and Health Sao Paulo Brazil"},{"name":"Department of Dermatology University of S\u00e3o Paulo Medical School Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cl\u00e1udia Nogueira","family":"Zerbini","sequence":"additional","affiliation":[{"name":"Department of Pathology University of S\u00e3o Paulo Medical School Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirian Nacagami","family":"Sotto","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of S\u00e3o Paulo Medical School Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila Aparecida Coelho","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Department of Pathology University of S\u00e3o Paulo Medical School Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"Sanches","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of S\u00e3o Paulo Medical School Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.3.800"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.15.1240"},{"key":"e_1_2_6_4_1","first-page":"354","article-title":"EORTC classification for primary cutaneous lymphomas; 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