{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:29:26Z","timestamp":1767857366479,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T00:00:00Z","timestamp":1443484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:p>Reactive lymphoid infiltrates of the skin composed predominantly of gamma\u2010delta (\u03b3\u03b4) T cells are not well described in the literature. Herein we report a case of an otherwise healthy 4\u2010year\u2010old male who presented with a waxing and waning papular rash characterized by small, discrete crusted papules spread across his trunk, face and extremities. Clinical evaluation revealed no evidence of systemic disease. Microscopic examination revealed a dermal, perivascular infiltrate of highly atypical lymphocytes with a \u03b3\u03b4 T cell phenotype, worrisome for primary cutaneous \u03b3\u03b4 T cell lymphoma. The clinical course, however, was that of a reactive condition and prompted consideration of a diagnosis of pityriasis lichenoides et varioliformis acuta (<jats:styled-content style=\"fixed-case\">PLEVA<\/jats:styled-content>) and lymphomatoid papulosis (<jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content>). In many ways, this case defies current classification schemes and seems to expand the spectrum of reactive \u03b3\u03b4 T cell infiltrates of the skin.<\/jats:p>","DOI":"10.1111\/cup.12601","type":"journal-article","created":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T08:27:54Z","timestamp":1439368074000},"page":"1012-1017","source":"Crossref","is-referenced-by-count":21,"title":["Atypical cutaneous \u03b3\u03b4 T cell proliferation with morphologic features of lymphoma but with clinical features and course of <scp>PLEVA<\/scp> or lymphomatoid papulosis"],"prefix":"10.1111","volume":"42","author":[{"given":"Rebecca L.","family":"King","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert C.","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debora R.","family":"Sekiguchi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,29]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31822067d1"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030584"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700003"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190500051893"},{"key":"e_1_2_4_6_1","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow SH","year":"2008"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb14840.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPMG37MXKYPUBE"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.8.1024"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2009.169"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-087288"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.03915.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.07.058"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.12.1483"},{"key":"e_1_2_4_15_1","first-page":"417","article-title":"Clonal T\u2010cell populations in pityriasis lichenoides et varioliformis acuta (Mucha\u2010Habermann disease)","volume":"126","author":"Weiss LM","year":"1987","journal-title":"Am J Pathol"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e75356"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.02.028"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.05.063"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04324.x"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12601","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:01:26Z","timestamp":1696291286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,29]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1111\/cup.12601"],"URL":"https:\/\/doi.org\/10.1111\/cup.12601","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,29]]}}}