{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T13:48:34Z","timestamp":1764510514110},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T00:00:00Z","timestamp":1441238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Angioinvasive (type E) lymphomatoid papulosis (<jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content>) is a recently described subtype of <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> presenting with eschar\u2010like lesions that can be mistaken for aggressive forms of angiocentric cutaneous T\u2010cell lymphoma. None of the cases of angioinvasive <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> described thus far have been associated with mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>). Herein, we describe a case of angioinvasive <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> type E coexisting with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>. The patient presented with an eschar on his chest and over time developed new nodules and large plaques with eschar formation, all of which resolved spontaneously over a period of a few weeks without intentional therapy. Biopsy revealed a <jats:styled-content style=\"fixed-case\">CD30<\/jats:styled-content>+ atypical inflammatory cell infiltrate with marked angiocentricity. Later, he developed erythematous annular scaly patches histologically consistent with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>. Our patient's clinical course confirms the indolent behavior characteristic of <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> despite the aggressive clinical and histologic appearance of lesions. The co\u2010occurrence of angioinvasive <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> in our patient highlights the propensity for <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> type E to coexist with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, as is characteristic of other <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> subtypes, and supports the theory that <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content> are related T\u2010cell lymphoproliferative disorders. Patients with <jats:styled-content style=\"fixed-case\">LyP<\/jats:styled-content> can present with large lesions exhibiting eschar formation and an atypical angiocentric\/angiodestructive lymphoid infiltrate and should be spared overtreatment.<\/jats:p>","DOI":"10.1111\/cup.12606","type":"journal-article","created":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T06:28:48Z","timestamp":1439533728000},"page":"1018-1023","source":"Crossref","is-referenced-by-count":16,"title":["New variant lymphomatoid papulosis type E preceding and coexisting with mycosis fungoides \u2013 a case report and review of the literature"],"prefix":"10.1111","volume":"42","author":[{"given":"Katrin","family":"Kiavash","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Louisville School of Medicine  Louisville KY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabra M.","family":"Abner","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Dermatology University of Louisville School of Medicine  Louisville KY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine C.","family":"Malone","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Louisville School of Medicine  Louisville KY USA"},{"name":"Department of Medicine, Division of Dermatology University of Louisville School of Medicine  Louisville KY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8635(18)30869-6"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1982.tb00331.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.4.441"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-011-0096-8"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.03024.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199606000-00001"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182648596"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2006.00548.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e318289b1db"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00081.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12243"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31825ba953"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.12.952"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182943394"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550410016949"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12606","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12606","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T00:01:28Z","timestamp":1696291288000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,3]]},"references-count":16,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["10.1111\/cup.12606"],"URL":"https:\/\/doi.org\/10.1111\/cup.12606","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,3]]}}}