{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:39:42Z","timestamp":1761709182176},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 CA 151306","K05 CA 104699","5T32AR056969"],"award-info":[{"award-number":["R01 CA 151306","K05 CA 104699","5T32AR056969"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2016,6]]},"abstract":"Backgrounds<\/jats:title>The diagnosis of melanoma can be challenging, especially in lesions for which the histopathologic criteria bridge two or more taxonomic categories. Newer genomic analytical methods of fluorescence in situ<\/jats:italic> hybridization (FISH<\/jats:styled-content>) and comparative genomic hybridization (CGH<\/jats:styled-content>) have been introduced as ancillary techniques to differentiate benign and malignant melanocytic proliferations.<\/jats:p><\/jats:sec>Methods<\/jats:title>We evaluated how pathologists perceive and are incorporating these new cytogenetic testing technologies into their practices. We conducted a study of 207 U.S. pathologists who interpret melanocytic lesions in clinical practice in 10 SEER<\/jats:styled-content> states. Pathologists were surveyed regarding perceptions and utilization of FISH<\/jats:styled-content> and\/or CGH<\/jats:styled-content> in their clinical practices.<\/jats:p><\/jats:sec>Results<\/jats:title>Results showed that 38% of pathologists use FISH<\/jats:styled-content> and\/or CGH<\/jats:styled-content> in interpreting melanocytic lesions. Pathologists reporting FISH<\/jats:styled-content> and\/or CGH<\/jats:styled-content> use were significantly younger (p < 0.05), were fellowship trained or board certified in dermatopathology (p < 0.001) and were affiliated with an academic institute (p < 0.001). Pathologists reporting that their colleagues consider them an expert in the assessment of melanocytic lesions were more likely to employ FISH<\/jats:styled-content> and\/or CGH<\/jats:styled-content> in their practices than non\u2010experts.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Early users of cytogenetic testing technologies in cutaneous pathology are more likely to be younger, affiliated with an academic institution and fellowship trained or board certified in dermatopathology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12705","type":"journal-article","created":{"date-parts":[[2016,3,12]],"date-time":"2016-03-12T07:15:12Z","timestamp":1457766912000},"page":"492-497","source":"Crossref","is-referenced-by-count":12,"title":["The self\u2010reported use of immunostains and cytogenetic testing in the diagnosis of melanoma by practicing U.S. pathologists of 10 selected states"],"prefix":"10.1111","volume":"43","author":[{"given":"Ge","family":"Zhao","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kachiu C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Massachusetts General Hospital Harvard University Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gina","family":"Kwon","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Frederick","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy L.","family":"Onega","sequence":"additional","affiliation":[{"name":"Department of Biomedical Data Science Norris Cotton Cancer Center Lebanon NH USA"},{"name":"Department of Epidemiology Norris Cotton Cancer Center Lebanon NH USA"},{"name":"Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Piepkorn","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine University of Washington School of Medicine Seattle WA USA"},{"name":"Dermatopathology Northwest Bellevue WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stevan","family":"Knezevich","sequence":"additional","affiliation":[{"name":"Pathology Associates Clovis CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond L.","family":"Barnhill","sequence":"additional","affiliation":[{"name":"Department of Pathology Faculty of Medicine, University of Paris Descartes Paris France"},{"name":"Institut Curie Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Elder","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Pennsylvania Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joann G.","family":"Elmore","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington School of Medicine Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2013.11.002"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10278-015-9836-y"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.07.027"},{"key":"e_1_2_5_5_1","unstructured":"ElmoreJG. Accuracy in the diagnosis of melanoma and the impact of double reading. Baseline Survey. URLhttp:\/\/sph.washington.edu\/faculty\/fac_bio.asp?url_ID=Elmore_Joann 2015[accessed on 25 February 2016]."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31824b1efd"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.228"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63536-5"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182753de6"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1442"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12705","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T19:25:47Z","timestamp":1695756347000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,7]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["10.1111\/cup.12705"],"URL":"https:\/\/doi.org\/10.1111\/cup.12705","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,7]]}}}