{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:53:41Z","timestamp":1790704421267,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T00:00:00Z","timestamp":1459382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute on Aging of the National Institutes of Health","award":["R01AG034676"],"award-info":[{"award-number":["R01AG034676"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2016,7]]},"abstract":"Background<\/jats:title>The association of atypical nevi with melanoma and other forms of skin cancer has not been clearly defined.<\/jats:p><\/jats:sec>Methods<\/jats:title>We studied 631 patients with first lifetime diagnosis of mild, moderate or severely atypical nevus from 2000 through 2005, identified through a population\u2010based approach.<\/jats:p><\/jats:sec>Results<\/jats:title>Age at first diagnosis differed significantly between men and women (p<.001). Incidence rates peaked in the second through fourth decades in women and in the third, sixth and seventh decades in men. From 2000 through 2005, the overall age\u2010 and sex\u2010adjusted incidence rate of all degrees of atypical nevi was 76.0 per 100,000 person\u2010years. There were no statistically significant associations identified between the degree of atypia and the future development of basal cell carcinoma, squamous cell carcinoma or MM<\/jats:styled-content> (p = 0.51, p = 0.28 and p = 0.19, respectively).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>There is no association between atypical nevi and the subsequent development of non\u2010melanoma skin cancer and MM<\/jats:styled-content>. Incidence rates of atypical nevi are higher among younger women and older men. The association between degree of atypia and malignant melanoma warrants further study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12709","type":"journal-article","created":{"date-parts":[[2016,3,12]],"date-time":"2016-03-12T07:27:58Z","timestamp":1457767678000},"page":"557-563","source":"Crossref","is-referenced-by-count":4,"title":["Incidence of atypical nevi in Olmsted County: an epidemiological study"],"prefix":"10.1111","volume":"43","author":[{"given":"Afolake","family":"Adaji","sequence":"first","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakriti","family":"Gaba","sequence":"additional","affiliation":[{"name":"Mayo Clinic College of Medicine, Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Lohse","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry D.","family":"Brewer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mayo Clinic Rochester MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90073-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2008.09.008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"350S","DOI":"10.1038\/jid.1993.62","article-title":"Risk of melanoma and other cancers in melanoma\u2010prone families","volume":"100","author":"Tucker MA","year":"1993","journal-title":"J Invest Dermatol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21208"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07466.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4065\/71.3.266"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2011.11.009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-09-0567"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1001\/jama.1997.03540420035026","article-title":"Clinically recognized dysplastic nevi: a central risk factor for cutaneous melanoma","volume":"14","author":"Tucker MA","year":"1997","journal-title":"JAMA"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(87)70230-8"},{"key":"e_1_2_6_12_1","first-page":"1171","article-title":"Retrospective studies and chart reviews","volume":"49","author":"Hess DR","year":"2004","journal-title":"Respir Care"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12709","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T09:26:49Z","timestamp":1695720409000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,31]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/cup.12709"],"URL":"https:\/\/doi.org\/10.1111\/cup.12709","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,31]]}}}