{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:42:33Z","timestamp":1780368153795,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,8,22]],"date-time":"2016-08-22T00:00:00Z","timestamp":1471824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Syringotropism is characterized by lymphocyte infiltration in the eccrine gland and is usually associated with various degrees of hyperplasia of eccrine gland cells. This phenomenon has been reported in rare cases of mycosis fungoides, which are also called as syringotropic mycosis fungoides.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We studied seven cases of lichen striatus associated with syringotropism and hyperplasia of eccrine gland cells, diagnosed at our dermatology department in the past 5 years. The hematoxylin and eosin\u2010stained slides from these cases were analyzed, and immunohistochemical and T\u2010cell receptor gene rearrangement studies were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the seven cases, two showed prominent and five showed subtle syringotropism and hyperplasia of eccrine gland cells. Immunohistochemical study showed mixed infiltration by T\u2010cells and B\u2010cells around the eccrine glands. The T\u2010cells were composed of <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content>\u2010positive cells. T\u2010cell receptor gene rearrangement study showed negative results in all the cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Syringotropism and hyperplasia of eccrine gland cells is a rare phenomenon in lichen striatus. Dermatopathologists should be aware of this to avoid misdiagnosis as syringotropic mycosis fungoides.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12768","type":"journal-article","created":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T11:10:00Z","timestamp":1468840200000},"page":"927-931","source":"Crossref","is-referenced-by-count":8,"title":["Lichen striatus with syringotropism and hyperplasia of eccrine gland cells: a rare phenomenon that should not be confused with syringotropic mycosis fungoides"],"prefix":"10.1111","volume":"43","author":[{"given":"Lei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University  Xian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengming","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University  Xian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University  Xian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwen","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University  Xian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Xijing Hospital Fourth Military Medical University  Xian China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182036ce7"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.06.033"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403202"},{"key":"e_1_2_5_5_1","first-page":"157","article-title":"Patchy alopecia, anhidrosis, eccrine gland wall hypertrophy and vasculitis","volume":"62","author":"Sarkany I","year":"1969","journal-title":"Proc R Soc Med"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1984.tb07318.x"},{"key":"e_1_2_5_7_1","first-page":"87","volume-title":"Neoplasms with eccrine differentiation","author":"Abenoza P","year":"1990"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000247579"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1979.tb01136.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.116.9.988a"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)70200-3"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1987.01660330113022"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1989.tb00032.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.12.011"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1993.tb01251.x"},{"key":"e_1_2_5_16_1","volume-title":"Histologic diagnosis of inflammatory skin diseases: an algorithmic method based on pattern analysis","author":"Ackerman AB","year":"2005"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1975.tb00825.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.280202.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0736-8046.2004.21302.x"},{"key":"e_1_2_5_20_1","first-page":"1048","article-title":"Lichen striatus histopathologically mimicking mycosis fungoides","volume":"12","author":"Mascolo M","year":"2014","journal-title":"J Dtsch Dermatol Ges"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12768","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T21:14:13Z","timestamp":1696367653000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,22]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/cup.12768"],"URL":"https:\/\/doi.org\/10.1111\/cup.12768","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,22]]}}}