{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T07:14:05Z","timestamp":1767597245850},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T00:00:00Z","timestamp":1472515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>Lymphomatoid papulosis (LyP) belongs to CD30+ lymphoproliferative disorders with indolent clinical course. Classic histological subtypes, A, B and C are characterized by the CD4+ phenotype, while CD8+ variants, most commonly classified as type D, were reported in recent years. We present 14 cases of CD8+ LyP. In all patients, self\u2010resolving or treatment\u2010sensitive papules were observed. Of 14 cases 7 produced results with typical microscopic features of LyP type D mimicking primary cutaneous aggressive epidermotropic CD8+ T\u2010cell lymphoma. The infiltration pattern in 4 of 14 cases were consistent with classic LyP type B, without CD30 expression in two cases, resembling mycosis fungoides (MF). The morphology of 2 of 14 cases shared a certain consistency with classic type A and C, lacking eosinophils and neutrophils. Extensive folliculotropism characteristic to type F was observed in 1 of 14 case. Significant MUM1 and PD1 expression were detected in 2 of 14 and 3 of 14 cases, respectively. We concluded that CD8+ LyP may present with different histopathological features compared with type D, similar to CD4+ LyP variants. Differential diagnoses include CD8+ papular MF, folliculotropic MF and anaplastic large cell lymphoma in addition to primary cutaneous aggressive epidermotropic T\u2010cell lymphoma. We emphasise that rare CD8+ LyP cases may exist with CD30\u2010negativity.<\/jats:p>","DOI":"10.1111\/cup.12779","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T08:06:39Z","timestamp":1469606799000},"page":"963-973","source":"Crossref","is-referenced-by-count":16,"title":["Histopathological aspects and differential diagnosis of <scp>CD8<\/scp> positive lymphomatoid papulosis"],"prefix":"10.1111","volume":"43","author":[{"given":"M\u00e1rta","family":"Marschalk\u00f3","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Dermatooncology Semmelweis University  Budapest Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00f3ra","family":"Gy\u00f6ngy\u00f6si","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Dermatooncology Semmelweis University  Budapest 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