{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:25:34Z","timestamp":1766269534022},"reference-count":43,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,9,15]],"date-time":"2016-09-15T00:00:00Z","timestamp":1473897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Cutaneous mantle cell lymphoma (MCL) is exceedingly rare, almost always occurring as a dissemination of systemic MCL. To date, only 32 cases have been described. We report a series of 10 cases of MCL in the skin, and provide a comprehensive clinicopathologic review with clinical follow\u2010up. Our cases occurred in older individuals (mean age = 70) and were more frequently in men (90%). Half of them presented in the head and neck region as a mass\/nodule, and the remainder in the trunk and extremities as nodules. All patients have stage IV disease. In two of the 10 cases (20%) the cutaneous lesions preceded the diagnosis of disseminated disease. In two of the seven cases with available clinical follow\u2010up information (33%) the skin was immediately involved after the diagnosis of MCL, and in three of the seven the skin was the first site of recurrence (mean interval = 57 months). The mean time to recurrence of the disease was 45.4 months and the overall survival was 66.3 months. Histologically six out of 10 cases (60%) had either pleomorphic or blastoid morphology (four out of 10 and two out of 10, respectively). The mean number of mitoses per 10 high\u2010power fields was 18.44. While nine out of 10 cases expressed cyclin\u2010D1, one case was not positive for cyclin\u2010D1 but did label with SOX\u201011. Limited cytogenetic data showed trisomy 14 in one case, in addition to the t(11;14) translocation.<\/jats:p>","DOI":"10.1111\/cup.12802","type":"journal-article","created":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T04:06:53Z","timestamp":1471579613000},"page":"1112-1120","source":"Crossref","is-referenced-by-count":13,"title":["Cutaneous mantle cell lymphoma: a clinicopathologic review of 10 cases"],"prefix":"10.1111","volume":"43","author":[{"given":"Alejandro A.","family":"Gru","sequence":"first","affiliation":[{"name":"Department of Pathology, Divisions of Dermatopathology and Hematopathology University of Virginia  Charlottesville VA USA"},{"name":"Department of Dermatology, Divisions of Dermatopathology and Hematopathology University of Virginia  Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Yadira","family":"Hurley","sequence":"additional","affiliation":[{"name":"Department of Dermatology Saint Louis University  St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea L.","family":"Salavaggione","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology The Ohio State University  Columbus OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey","family":"Brodell","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Rochester  Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Sheinbein","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Dermatology Washington University, School of Medicine  St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan","family":"Anadkat","sequence":"additional","affiliation":[{"name":"Department of Internal 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