{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,5]],"date-time":"2025-07-05T09:04:36Z","timestamp":1751706276907},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T00:00:00Z","timestamp":1481500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>Cutaneous polyarteritis nodosa (<jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content>) is a chronic, indolent, single organ arteritis that generally presents with lower extremity nodules and\/or livedo racemosa, accompanied by malaise and arthralgias. <jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content> is often triggered by infection, commonly Group A streptococcal species, and is considered an autoimmune reaction. Scarring from surgery and obliterative lymphangiitis from bacterial cellulitis are the causes of lymphedema. Lymphedematous skin is predisposed to autoimmune disorders. Herein we report a 53\u2010year\u2010old woman who developed <jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content> restricted to a localized area of the right upper arm\u2013shoulder that had undergone multiple surgeries, complicated by episodes of <jats:italic>Streptococcus viridans<\/jats:italic> cellulitis. Clinically, a 15\u2009cm diameter plaque exhibited violaceous, reticulate margins, subtle papules and nodules and central livedo racemosa. Biopsy showed numerous foci of arteritis in active, subacute and reparative stages. In addition, a broad zone of fibrosis replaced the deep dermis\u2010subcutis zone and harbored numerous dilated lymphatic vessels scar lymphedema. Treatment consisted of high potency topical corticosteroids under occlusion; remission after 3\u2009months therapy and follow\u2010up. <jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content> primarily affects the lower legs, a region of frequently affected by phlebolymphedema. This report of <jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content> localized to an area of scar lymphedema underscores the importance of lymphatic function in the pathogenesis of <jats:styled-content style=\"fixed-case\">CPAN<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cup.12861","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T12:01:08Z","timestamp":1478779268000},"page":"210-216","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous polyarteritis nodosa localized to a region of lymphedema secondary to <i>Streptococcus viridans<\/i> cellulitis and multiple surgeries"],"prefix":"10.1111","volume":"44","author":[{"given":"Andrew","family":"Matsumoto","sequence":"first","affiliation":[{"name":"Department of Pathology Albany Medical College  Albany NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami N.","family":"Al\u2010Rohil","sequence":"additional","affiliation":[{"name":"Department of Pathology Albany Medical College  Albany NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Bravin","sequence":"additional","affiliation":[{"name":"Department of Pathology Bassett Healthcare Network  Cooperstown NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Pathology Bassett Healthcare Network  Cooperstown NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Wroblewski","sequence":"additional","affiliation":[{"name":"Wadsworth Center New York State Department Health  Albany NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Pathology Albany Medical College  Albany NY 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