{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:06:15Z","timestamp":1758823575574,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T00:00:00Z","timestamp":1485993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>For the past decades, hydrophilic polymer gel coating have been widely used on endovascular devices to decrease friction and to aid with binding and delivering of medications in drug\u2010eluting stents. In the recent years, hydrophilic polymer emboli disease has been recognized as an iatrogenic adverse effect which has led to considerable morbidity and mortality of patients. This under\u2010recognized embolic phenomenon now has reproducible pathognomonic histologic findings. Small\u2010 to medium\u2010sized blood vessels are occluded with basophilic, amorphous, non\u2010refractile, non\u2010polarizable and whirled aggregates of foreign body material. Depending on the affected organ, the patients have variable symptomatology, from livedo racemosa, gangrene of extremities to cardiac arrhythmias, hemiparesis, stroke and death. Here, we present a unique case of hydrophilic polymer vasculopathy 6\u2009years post\u2010endovascular procedure with coinciding pseudoxanthoma elasticum\u2010like changes. As the literature has seen increased reporting of individual cases and case series documenting the patients\u2019 diverse symptomatology; hydrophilic polymer vasculopathy should be entertained sooner in the patient's differential diagnosis.<\/jats:p>","DOI":"10.1111\/cup.12889","type":"journal-article","created":{"date-parts":[[2016,12,30]],"date-time":"2016-12-30T07:56:40Z","timestamp":1483084600000},"page":"393-396","source":"Crossref","is-referenced-by-count":3,"title":["Hydrophilic polymer vasculopathy with coinciding pseudoxanthoma elasticum\u2010like changes in an amputated toe"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4237-767X","authenticated-orcid":false,"given":"Silvija P.","family":"Gottesman","sequence":"first","affiliation":[{"name":"Ackerman Academy of Dermatopathology  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Department of Pathology SUNY Downstate Medical Center  Brooklyn New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raavi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Pathology SUNY Downstate Medical Center  Brooklyn New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,2]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.74"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12420"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2006.00705.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.238"},{"key":"e_1_2_4_6_1","unstructured":"Boston Scientific. 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