{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T23:03:34Z","timestamp":1789772614749,"version":"4.0.1"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>We present herein a series of 14 lesions showing overlapping features with the newly defined benign cutaneous mesenchymal neoplasm labeled as fibroblastic connective tissue nevus (<jats:styled-content style=\"fixed-case\">FCTN<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Total of 8 patients were male and 5 were female, ranging in age from 1 to 56 years. Lesions appeared as isolated nodules or plaques on the trunk (7 cases), the limbs (4 cases) and the neck (2 cases). Histologically, all cases were composed of bundles of bland spindle cells of fibroblastic\/myofibroblastic lineage irregularly branching within the reticular dermis and along fibrous septa in the subcutis. Adnexal structures and dermal adipocytes were entrapped by the fascicles, the epidermis was often papillomatous and elastic fibers were decreased and fragmented. Expression of <jats:styled-content style=\"fixed-case\">CD34<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ASMA<\/jats:styled-content> was found in 8 and 7 cases, respectively. Follow\u2010up was available for 7 patients (mean follow\u2010up, 5 years; range, 1\u201010 years). None of the cases metastasized or recurred, even when incompletely excised.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The differential diagnosis of <jats:styled-content style=\"fixed-case\">FCTN<\/jats:styled-content> is broad and includes hypertrophic scar, dermatofibroma, dermatomyofibroma, pilar leiomyoma, plaque\u2010stage <jats:styled-content style=\"fixed-case\">DFSP<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">CD34<\/jats:styled-content>\u2010positive plaque\u2010like dermal fibroma, fibroblastic\u2010predominant plexiform fibrohistiocytic tumor, lipofibromatosis, superficial desmoid fibromatosis and fibrous hamartoma of infancy, of which it represents probably the monophasic variant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.12993","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T18:18:02Z","timestamp":1497982682000},"page":"827-834","source":"Crossref","is-referenced-by-count":18,"title":["Fibroblastic connective tissue nevus: Clinicopathological and immunohistochemical study of 14 cases"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4390-0706","authenticated-orcid":false,"given":"Ilaria","family":"Pennacchia","sequence":"first","affiliation":[{"name":"Institute of Pathology Catholic University of the Sacred Heart  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinz","family":"Kutzner","sequence":"additional","affiliation":[{"name":"Dermopathologie Bodensee  Friedrichshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1893-535X","authenticated-orcid":false,"given":"Dmitry V.","family":"Kazakov","sequence":"additional","affiliation":[{"name":"Sikl's Department of Pathology Medical Faculty in Pilsen, Charles University in Prague  Pilsen Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mentzel","sequence":"additional","affiliation":[{"name":"Dermopathologie Bodensee  Friedrichshafen 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