{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:41:30Z","timestamp":1790800890870,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,9,15]],"date-time":"2017-09-15T00:00:00Z","timestamp":1505433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Psoriasis is usually diagnosed clinically, so only non\u2010classic or refractory cases tend to be biopsied. Diagnostic uncertainty persists when dermatopathologists encounter features regarded as non\u2010classic for psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Define and document classic and non\u2010classic histologic features in skin biopsies from patients with clinically confirmed psoriasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Minimal clinical diagnostic criteria were informally validated and applied to a consecutive series of biopsies histologically consistent with psoriasis. Clinical confirmation required 2 of the following criteria: (1) classic morphology, (2) classic distribution, (3) nail pitting, and (4) family history, with #1 and\/or #2 as 1 criterion in every case<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty\u2010one biopsies from 46 patients were examined. Classic features of psoriasis included hypogranulosis (96%), club\u2010shaped rete ridges (96%), dermal papilla capillary ectasia (90%), Munro microabscess (78%), suprapapillary plate thinning (63%), spongiform pustules (53%), and regular acanthosis (14%). Non\u2010classic features included irregular acanthosis (84%), junctional vacuolar alteration (76%), spongiosis (76%), dermal neutrophils (69%), necrotic keratinocytes (67%), hypergranulosis (65%), neutrophilic spongiosis (61%), dermal eosinophils (49%), compact orthokeratosis (37%), papillary dermal fibrosis (35%), lichenoid infiltrate (25%), plasma cells (16%), and eosinophilic spongiosis (8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Psoriasis exhibits a broader histopathologic spectrum. The presence of some non\u2010classic features does not necessarily exclude the possibility of psoriasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cup.13033","type":"journal-article","created":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T10:26:48Z","timestamp":1503397608000},"page":"1018-1026","source":"Crossref","is-referenced-by-count":56,"title":["Psoriasis or not? Review of 51 clinically confirmed cases reveals an expanded histopathologic spectrum of psoriasis"],"prefix":"10.1111","volume":"44","author":[{"given":"Thinh","family":"Chau","sequence":"first","affiliation":[{"name":"Department of Dermatology University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kory K.","family":"Parsi","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maija","family":"Kiuru","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Davis School of Medicine  Sacramento California"},{"name":"Department of Pathology and Laboratory Medicine University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Konia","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Davis School of Medicine  Sacramento California"},{"name":"Department of Pathology and Laboratory Medicine University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin\u2010Shang","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, Department of Public Health Sciences University of California, Davis School of Medicine  Sacramento California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1771-8257","authenticated-orcid":false,"given":"Maxwell 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California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.11.013"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1085-5629(99)80005-4"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-012-8305-3"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.01.008"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02245.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1972.01620130035008"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2007.08.005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.1074.146"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1994.tb01073.x"},{"key":"e_1_2_6_11_1","volume-title":"Weedon's 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