{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T23:10:33Z","timestamp":1789513833114,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T00:00:00Z","timestamp":1505779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:p>Lipodermatosclerosis (<jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content>) is a well\u2010recognized form of fibrosing panniculitis. Although chronic cases are readily diagnosed, early and evolving lesions may be clinically mistaken for cellulitis and other forms of panniculitis. Most pathologists are familiar with a pseudomembranous type of fat necrosis as a useful feature of chronic <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content>. Although nonspecific, this distinctive pattern of fat necrosis helps in supporting a diagnosis of <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content> in the appropriate clinical context. The histopathologic features of early and evolving <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content> and those involving the dermis are less well documented. We report a case of early <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content> showing extensive pseudomembranous changes in the dermis on a superficial skin biopsy where progression to a classic established lesion was documented clinically. We suspect that this previously unreported and unusual finding may be a histopathologic clue for evolving lesions of <jats:styled-content style=\"fixed-case\">LDS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/cup.13038","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T15:16:41Z","timestamp":1504624601000},"page":"1070-1074","source":"Crossref","is-referenced-by-count":3,"title":["Pseudomembranous changes in the dermis: A novel observation and potential clue for evolving lipodermatosclerosis?"],"prefix":"10.1111","volume":"44","author":[{"given":"Adane","family":"Ayele","sequence":"first","affiliation":[{"name":"Department of Dermatovenereology Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Tidman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Royal Infirmary of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0142-9135","authenticated-orcid":false,"given":"Asok","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Pathology Western General Hospital and the University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2010.01338.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01049.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12856"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70085-8"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90681-7"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.10.048"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.119101"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2008.05.011"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.04510010122016"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1986.tb00475.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198601000-00007"},{"key":"e_1_2_5_13_1","first-page":"823","article-title":"Incidence of membranous lipodystrophy\u2010like change among patients with limb necrosis caused by chronic arterial obstruction","volume":"108","author":"Machinami R","year":"1984","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70156-3"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2002.290102.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246087"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06243.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734602001002002"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13038","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T13:21:23Z","timestamp":1695561683000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,19]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/cup.13038"],"URL":"https:\/\/doi.org\/10.1111\/cup.13038","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,19]]}}}