{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T11:18:50Z","timestamp":1784719130854,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,10]],"date-time":"2017-12-10T00:00:00Z","timestamp":1512864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Epithelioid benign fibrous histiocytoma has been considered a variant of fibrous histiocytoma, but is now considered a distinct entity, typically showing ALK expression. Most show typical morphological features, including an epidermal collarette and large, bland, epithelioid cells. We have recently encountered 2 examples showing an unusual pattern of pericellular calcification, a previously unreported finding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Available slides were reviewed and clinical follow\u2010up was obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>These lesions occurred on the chins of a 16\u2010year\u2010old and 19\u2010year\u2010old female and showed prominent pericellular calcification in addition to otherwise\u2010typical features of epithelioid fibrous histiocytoma. By immunohistochemistry, both lesions were intensely positive for ALK protein. Clinical follow\u2010up (available for 1 case) showed the patient to be disease\u2010free 5\u2009months after excision.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To the best of our knowledge, epithelioid fibrous histiocytomas showing \u201cchondroblastoma\u2010like\u201d calcification have not been previously reported. The chief significance of this finding seems to be in its potential for confusion with other calcifying tumors of the skin and subcutis. Awareness that epithelioid fibrous histiocytomas may show this unusual morphological finding, careful morphological evaluation and ancillary immunohistochemical studies, including ALK protein, should allow for their confident diagnosis in essentially all instances.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.13068","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T11:02:35Z","timestamp":1508929355000},"page":"99-103","source":"Crossref","is-referenced-by-count":10,"title":["\u201cChondroblastoma\u2010like\u201d epithelioid fibrous histiocytoma: A previously undescribed and potentially confusing variant"],"prefix":"10.1111","volume":"45","author":[{"given":"Anthony P.","family":"Martinez","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2428-8072","authenticated-orcid":false,"given":"Youran","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic Foundation  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2278-5908","authenticated-orcid":false,"given":"Steven D.","family":"Billings","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic Foundation  Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-7351","authenticated-orcid":false,"given":"Andrew L.","family":"Folpe","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,10]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb07782.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13548"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70034-D"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.49"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2011.01747.x"},{"issue":"3","key":"e_1_2_4_7_1","first-page":"98","article-title":"Epithelioid fibrous histiocytoma EMA positivity: a case report","volume":"105","author":"Floris C","year":"2013","journal-title":"Pathologica"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2012.01944.x"},{"issue":"2","key":"e_1_2_4_9_1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00000372-199004000-00003","article-title":"Cell differentiation in benign cutaneous fibrous histiocytomas. An immunohistochemical study with antibodies to histiomonocytic cells and intermediate filament proteins","volume":"12","author":"Soini Y","year":"1990","journal-title":"Am J Dermatopathol"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2015.83"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAI.0000000000000238"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12372"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12255"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197011)26:5<1029::AID-CNCR2820260510>3.0.CO;2-R"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1994.tb00547.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896909352862"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.175"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181882c54"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199804000-00020"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200103000-00009"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2003.08.016"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182772bba"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2011.108"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196409)17:9<1203::AID-CNCR2820170917>3.0.CO;2-7"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197804)41:4<1414::AID-CNCR2820410429>3.0.CO;2-O"},{"key":"e_1_2_4_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200105000-00015"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200304000-00001"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182284a3f"},{"key":"e_1_2_4_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199304000-00011"},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1992.tb01358.x"},{"key":"e_1_2_4_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000555"},{"key":"e_1_2_4_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31827f0a6f"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13068","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:46:24Z","timestamp":1695570384000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,10]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/cup.13068"],"URL":"https:\/\/doi.org\/10.1111\/cup.13068","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,10]]}}}