{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T22:14:51Z","timestamp":1782339291808,"version":"3.54.5"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,17]],"date-time":"2017-12-17T00:00:00Z","timestamp":1513468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p>Proximal\u2010type epithelioid sarcoma (ES) with a diffuse myxoid stroma is rare. Here, we report the case of a 33\u2010year\u2010old man with a perineal mass. Imaging showed the presence of a poorly demarcated 6.9\u2009\u00d7\u20095.3\u2010cm mass in the subcutaneous perineal region. Macroscopic examination showed that the resected tissues were partially necrotic. Histological examination showed that the tumor comprised numerous large or pleomorphic epithelioid cells with large vesicular nuclei and prominent nucleoli. A clear background of necrosis and inflammatory exudates was also present. Immunohistochemical examination showed that the tumor cells were positive for vimentin and CD34\u200a\u2014\u200aboth of which were expressed throughout the cytoplasm\u200a\u2014\u200abut typically did not express nuclear INI1 (SMARCB1). Hematoxylin\u2010eosin staining (HE staining) showed that the mucin content of the tumor was approximately 80%. The patient was diagnosed with proximal\u2010type ES with myxoid features. The patient died due to disease progression after 2\u2009months of follow\u2010up and without undergoing further treatment in our department. To our knowledge, only 2 cases of proximal\u2010type ES with diffuse myxoid stroma have been reported. Proximal\u2010type ES is rare, and this is the first case report of proximal ES with myxoid features in the perineal area.<\/jats:p>","DOI":"10.1111\/cup.13069","type":"journal-article","created":{"date-parts":[[2017,10,25]],"date-time":"2017-10-25T12:02:42Z","timestamp":1508932962000},"page":"151-155","source":"Crossref","is-referenced-by-count":6,"title":["Clinicopathological analysis of myxoid proximal\u2010type epithelioid sarcoma"],"prefix":"10.1111","volume":"45","author":[{"given":"Yanyang","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology The Third Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4806-1254","authenticated-orcid":false,"given":"Furong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of General Surgery The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Pathology The Third Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Pathology The Third Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pathology The Third Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pathology The Third Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,17]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197011)26:5<1029::AID-CNCR2820260510>3.0.CO;2-R"},{"key":"e_1_2_4_3_1","volume-title":"WHO Classification of Tumors of Soft Tissue and Bone","author":"Fletcher CDM","year":"2013"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199702000-00002"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880368"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2010.03688.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02303673"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/13577140310001644760"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21630"},{"key":"e_1_2_4_10_1","doi-asserted-by":"crossref","DOI":"10.1097\/JTO.0b013e31829e7f16","article-title":"A case of pleural epithelioid sarcoma of proximal type presenting as malignant pleural mesothelioma","volume":"8","author":"Madsen GA","year":"2013","journal-title":"J Thorac Oncol"},{"key":"e_1_2_4_11_1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.4172\/2324-9110.1000106","article-title":"Proximal\u2010type epithelioid sarcoma of the head and neck (HN): a Study with Immunohistochemical and Molecular Analysis of SMARCB1","volume":"2","author":"Frank R","year":"2013","journal-title":"J Clin Exp Oncol"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2016.09.024"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1999.00835.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000102"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.2001.1311d.x"},{"key":"e_1_2_4_16_1","volume-title":"AFIP Atlas of Tumor Pathology Series 4\u2010Tumors of the Soft Tissues. Maryland","author":"Markku Miettinen M","year":"2014"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200108000-00011"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318206b67b"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800065"},{"key":"e_1_2_4_20_1","first-page":"135","article-title":"Impact of SYT\u2010SSX fusion type on the clinical behavior of synovial sarcoma: a multi\u2010institutional retrospective study of 243 patients","volume":"62","author":"Ladanyi M","year":"2002","journal-title":"Cancer Res"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-2264(2000)9999:9999<::AID-GCC1056>3.0.CO;2-G"},{"issue":"12","key":"e_1_2_4_22_1","first-page":"805","article-title":"Extraenal malignant rhabdoid tumor of children: a clinicopathologic analysis of 8 cases","volume":"43","author":"Wang H","year":"2014","journal-title":"Zhonghua Bing Li Xue Za Zhi"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13069","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:47:07Z","timestamp":1695570427000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,17]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/cup.13069"],"URL":"https:\/\/doi.org\/10.1111\/cup.13069","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,17]]}}}