{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:42:20Z","timestamp":1784335340430,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,3,12]],"date-time":"2018-03-12T00:00:00Z","timestamp":1520812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:p>Radiation\u2010induced sarcoma (RIS) is an unusual but well documented tumor. The frequency of RIS of the head and neck region has been reported as 0.143%. In the literature the median interval between irradiation and development of sarcoma is 11 years. Cases of RIS with a short latent period, that is, less than 4 years are rare. We report a case of a 34\u2010year\u2010old female who developed an osteosarcoma of the scalp, over a previous craniotomy scar, 3 years after excision of a frontal anaplastic oligodendroglioma which had been followed by a course of 6\u2009weeks radiotherapy (58\u2009Gy) and 6 cycles of temozolomide. The histological features were those of a high\u2010grade osteosarcoma with epidermotropism of tumor cells. Lymph nodes were partially replaced by high\u2010grade metastatic osteosarcoma, with extra\u2010nodal lymphatic tumor thrombi. To our knowledge the only other case report of post\u2010radiation osteosarcoma with a short latency period was a case of osteosarcoma in the craniofacial bone 3 years after radiotherapy for maxillary squamous cell carcinoma. The histological finding of prominent replacement of the epidermis by osteosarcoma has not been reported before.<\/jats:p>","DOI":"10.1111\/cup.13103","type":"journal-article","created":{"date-parts":[[2018,1,13]],"date-time":"2018-01-13T13:45:12Z","timestamp":1515851112000},"page":"352-354","source":"Crossref","is-referenced-by-count":10,"title":["A case of radiation\u2010induced osteosarcoma of the skull presenting as a cutaneous epidermotropic tumor with a short latent period"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1548-5528","authenticated-orcid":false,"given":"Elham","family":"Rashidghamat","sequence":"first","affiliation":[{"name":"St. John's Institute of Dermatology Guy's and St Thomas\u2019 NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime Eduardo","family":"Calonje","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology Guy's and St Thomas\u2019 NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,12]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"623","article-title":"Zur Frage des Rontgensarkoms, zugleich ein Beitrag zur Pathogenese des Sarkoms","volume":"69","author":"Beck A","year":"1922","journal-title":"Munch Med Wochenschr"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/20938070"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2008.11.008"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930801)72:3<887::AID-CNCR2820720338>3.0.CO;2-5"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1971)28:5<1087::AID-CNCR2820280502>3.0.CO;2-F"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910801)68:3<524::AID-CNCR2820680313>3.0.CO;2-E"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2003.01427.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841860802047387"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.1728"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.89B6.18729"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01374.x"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:57:58Z","timestamp":1695571078000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,12]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.1111\/cup.13103"],"URL":"https:\/\/doi.org\/10.1111\/cup.13103","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,12]]}}}