{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T21:16:13Z","timestamp":1782940573355,"version":"3.54.5"},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T00:00:00Z","timestamp":1524441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2018,7]]},"abstract":"Background<\/jats:title>There are patients with recalcitrant psoriasiform plaques that do not fit into conventional categories of facial dermatoses. Our study aims to describe the clinicopathological characteristics of several patients with a unique presentation of persistent psoriasiform facial rashes.<\/jats:p><\/jats:sec>Methods<\/jats:title>This retrospective cross\u2010sectional study analyzed clinical and histological data of known cases of recalcitrant psoriasiform dermatosis of the face diagnosed at National Skin Centre, Singapore, over 10\u2009years.<\/jats:p><\/jats:sec>Results<\/jats:title>There were 8 Chinese patients with mean age at onset of 29 years. Majority had pink to pink\u2010orange well\u2010defined plaques with dry scale (n<\/jats:italic>\u2009=\u20096, 75%), distributed mostly on the cheeks (100%) and chin (n<\/jats:italic>\u2009=\u20097, 88%). Hyperkeratosis, parakeratosis, preserved granular layer and psoriasiform hyperplasia were showed in all biopsies. Other common findings included subtle subcorneal acantholysis, \u201ccheckerboard\u201d alternating ortho\u2010\/parakeratosis, vacuolated keratinocytes and follicular plugging. All patients showed little treatment response. One patient eventually developed features of type II pityriasis rubra pilaris (PRP). Our study was limited by its small sample size and lack of a pre\u2010existing diagnostic code.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>This recalcitrant psoriasiform facial dermatosis seems to be a distinct entity, with consistent and reproducible clinical features and a PRP\u2010like histology, bearing some resemblance to the recently described condition\u2014facial discoid dermatosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.13148","type":"journal-article","created":{"date-parts":[[2018,3,31]],"date-time":"2018-03-31T14:57:52Z","timestamp":1522508272000},"page":"491-497","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Recalcitrant psoriasiform dermatosis of the face: Is it related to pityriasis rubra pilaris?"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4891-0831","authenticated-orcid":false,"given":"Emily Yiping","family":"Gan","sequence":"first","affiliation":[{"name":"National Skin Centre Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"See Ket","family":"Ng","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee Leok","family":"Goh","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siong See Joyce","family":"Lee","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01279.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.04990.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199006000-00060"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1997.tb00816.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1996.tb01478.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(86)70123-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3315\/jdcr.2012.1107"},{"issue":"10","key":"e_1_2_6_9_1","first-page":"978","article-title":"Pityriasis rubra pilaris with epidermolytic hyperkeratosis","volume":"7","author":"Doughty LE","year":"2008","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.04206.x"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13148","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:05:35Z","timestamp":1695499535000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,23]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1111\/cup.13148"],"URL":"https:\/\/doi.org\/10.1111\/cup.13148","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,23]]},"assertion":[{"value":"2018-02-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}