{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:44:18Z","timestamp":1773391458129,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T00:00:00Z","timestamp":1526428800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>A 19\u2010year\u2010old man suffering from testicular choriocarcinoma presented to the dermatology department with a cutaneous metastasis on his head. This metastasis was the first sign of disease that led to medical consultation. Histopathology revealed cytotrophoblasts and syncytiotrophoblasts, the later expressing human chorionic gonadotropin antigen. Whole body computed tomography showed multiple metastases of the brain, lung, liver, bone, paraaortic lymph nodes and left uvea; the primary was found in the left testicle. Despite neurosurgical intervention and chemotherapy the patient died 9 days after the biopsy of the cutaneous metastasis. Cutaneous metastases of testicular choriocarcinoma are exceptionally rare, with fewer than a dozen cases reported in the English\u2010language literature. The present case highlights that testicular choriocarcinoma metastatic to the skin should be included in the differential of cutaneous scalp tumors.<\/jats:p>","DOI":"10.1111\/cup.13261","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T18:10:32Z","timestamp":1523988632000},"page":"535-538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Testicular choriocarcinoma with cutaneous metastasis in a 19\u2010year\u2010old man"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2153-4952","authenticated-orcid":false,"given":"Ferdinand","family":"Toberer","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Medical Center, Ruprecht\u2010Karls\u2010University  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Enk","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Medical Center, Ruprecht\u2010Karls\u2010University  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Hartschuh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Medical Center, Ruprecht\u2010Karls\u2010University  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carsten","family":"Gr\u00fcllich","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology National Center for Tumor Diseases, University of Heidelberg  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,5,16]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199612000-00016"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1995.tb01423.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-005-1664-4"},{"issue":"3","key":"e_1_2_4_5_1","first-page":"e77","article-title":"Pure choriocarcinoma of testis with rare gingival and skin metastases","volume":"48","author":"Bhatia K","year":"2007","journal-title":"Singap Med J"},{"key":"e_1_2_4_6_1","first-page":"119","article-title":"Skin metastases in cancer patients","volume":"39","author":"Spencer PS","year":"1987","journal-title":"Cutis"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO;2-7"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181c0e127"},{"issue":"2","key":"e_1_2_4_9_1","first-page":"117","article-title":"Testicular choriocarcinoma metastatic to the skin: an additional case and literature review","volume":"67","author":"Tinkle LL","year":"2001","journal-title":"Cutis"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.101760"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2007.10.006"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1991.tb03984.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(89)90276-8"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13261","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T20:06:04Z","timestamp":1695499564000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,16]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1111\/cup.13261"],"URL":"https:\/\/doi.org\/10.1111\/cup.13261","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,16]]},"assertion":[{"value":"2018-03-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}