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She had taken oral contraceptives for several years and stopped 1 year prior to presentation. Histologically, the tumor was composed of small and compressed venous structures infiltrating in the dermis and subcutis. Immunohistochemically, the tumor cells displayed negative immunoreactivity for human herpesvirus\u20108 and positive immunoreactivity for smooth muscle actin and progesterone receptor (PR). Taken together with the patient's medical hormone therapy history and the evidence of PR immunoreactivity, our findings support that progesterone may be associated with the tumorigenesis of MVH.<\/jats:p>","DOI":"10.1111\/cup.13322","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T01:12:14Z","timestamp":1531962734000},"page":"847-850","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A microvenular hemangioma with a rare expression of progesterone receptor immunocreativity and a review of the literature"],"prefix":"10.1111","volume":"45","author":[{"given":"Yi\u2010Chen","family":"Juan","sequence":"first","affiliation":[{"name":"Department of Dermatology Changhua Christian Hospital  Changhua Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih\u2010Jung","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology 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