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These findings are non\u2010specific, and the diagnosis is based on clinicopathologic correlation and serology results. However, variation in clinical presentation, serology, and histology can make the diagnosis difficult and requires cognizance of uncommon findings that may serve as a clue to the diagnosis. Herein, we report such a case with unusual histologic features of vascular damage and deep dermal necrosis in a seronegative patient who presented with clinical features of anti\u2010MDA5 variant of dermatomyositis.<\/jats:p>","DOI":"10.1111\/cup.13324","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T08:05:10Z","timestamp":1532419510000},"page":"851-854","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Seronegative dermatomyositis presenting with features of anti\u2010MDA5 subtype"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8934-4800","authenticated-orcid":false,"given":"Aadil","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Pathology Loyola University Medical Center  Maywood Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Scarborough","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8304-2019","authenticated-orcid":false,"given":"Rosa","family":"Gabriela","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony P.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"},{"name":"Department of Dermatology Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilma","family":"Bergfeld","sequence":"additional","affiliation":[{"name":"Department of Pathology Cleveland Clinic  Cleveland Ohio"},{"name":"Department of Dermatology Cleveland Clinic  Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,15]]},"reference":[{"volume-title":"Pathology and Immunopathology of Dermatomyositis. 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