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Two of them were initially diagnosed as classical Hodgkin lymphoma (cHL), on the other hand, the last one as a B\u2010cell lymphoma. All patients have been treated for angioimmunoblastic T\u2010cell lymphoma (AITL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a second review of the skin biopsies with further immunophenotypic molecular analyses. Scrupulous observation revealed, in the background of the three cases, atypical small to medium\u2010sized lymphocytes carrying a CD3+, CD4+ T\u2010cell phenotype and expressing PD1 and CXCL13 follicular helper T\u2010cell markers. The two lesions initially diagnosed as cHL showed scattered HRS\u2010like cells with CD30+, CD15+, PAX5+, CD20\u2212, Epstein Barr Virus (EBV) + classical phenotype. The case initially diagnosed as B\u2010cell lymphoma showed a diffuse B\u2010cell proliferation associated with small B\u2010cell and medium to large\u2010sized B blasts that were positive for EBV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Those cases highlighted that atypical T\u2010cells may be obscured by B\u2010cell proliferation mimicking cHL or B\u2010cell lymphoma in cutaneous localization of AITL and confirmed the requirement of collecting clinical information before performing a diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.13382","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T06:43:23Z","timestamp":1540795403000},"page":"102-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Cutaneous localization of angioimmunoblastic T\u2010cell lymphoma may masquerade as B\u2010cell lymphoma or classical Hodgkin lymphoma: A histologic 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