{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:03:07Z","timestamp":1766268187195,"version":"3.40.5"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:00:00Z","timestamp":1553817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Granulomatous mycosis fungoides (MF) is a rare variant in which granulomas are associated with other typical signs of MF. Its prognosis is worse than that of classical MF. Plasmacytoid dendritic cells (PDCs) are a subset of interferon\u2010producing dendritic cells that link the innate and the adaptative immune responses. They have also been related to tolerance to certain tumors such as melanoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>In this article, we examined for the presence of CD123+ PDC in six cases of granulomatous MF from our archives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found clusters of 10 or more positive cells in three of six cases of granulomatous MF (two women and a man, in their sixth and seventh decade). Although in two of these three cases the granulomatous response was extensive, in the other, it only represented 10% of the infiltrate of the biopsy. In all three cases, the granulomas were epithelioid, sarcoidal type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CD123+ PDC can be identified in granulomatous MF. The pathogenic and prognostic role of this finding requires further clarification.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.13438","type":"journal-article","created":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T05:10:33Z","timestamp":1549602633000},"page":"335-342","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Plasmacytoid dendritic cells in granulomatous variant of mycosis fungoides"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6617-2364","authenticated-orcid":false,"given":"Angel","family":"Fernandez\u2010Flores","sequence":"first","affiliation":[{"name":"Department of Cellular Pathology Hospital El Bierzo  Ponferrada Spain"},{"name":"Department of CellCOM\u2010ST Group, Biomedical Investigation Institute of A Coru\u00f1a, CellCOM\u2010ST Group  A Coru\u00f1a Spain"},{"name":"Department of Cellular Pathology Hospital de la Reina  Ponferrada 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