{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T15:12:54Z","timestamp":1785683574475,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T00:00:00Z","timestamp":1556841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Secondary cutaneous involvement by mantle cell lymphoma (MCL), an uncommon aggressive B\u2010cell malignancy, predominantly involves the dermis, with few reports of pannicular involvement. Lymphocytic infiltration of subcutaneous tissue is associated with inflammatory panniculitides and certain T\u2010cell lymphomas, primarily subcutaneous panniculitis\u2010like T\u2010Cell lymphoma (SPTCL), which is characterized by rimming of adipocytes by tumor cells. We report the case of a 69\u2010year\u2010old man with a history of systemic nodal MCL who presented with subcutaneous nodules on his lower extremities after receiving multi\u2010agent chemotherapy. Biopsies showed a dense infiltrate of atypical, mitotically active, monomorphic, medium\u2010sized lymphoid cells in the subcutaneous fat with prominent rimming of the adipocytes by the tumor cells. These features were not morphologically typical of MCL. Immunohistochemistry showed these cells to be CD20+, CD5+ B\u2010cells with strong cyclin D1 expression; fluorescence in situ hybridization (FISH) analysis was positive for t(11;14)(q13;32), confirming the diagnosis of secondary cutaneous involvement of MCL. This represents an exceptional report of cutaneous MCL presenting clinically and histologically with a panniculitis\u2010type pattern and adipocyte rimming, histomorphologically mimicking SPTCL. Noteworthy examples, such as this report, support the practice of utilizing clinical correlation, immunohistochemistry, and\/or molecular cytogenetics to confirm the diagnosis of any case suspicious for cutaneous lymphoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cup.13471","type":"journal-article","created":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T07:59:29Z","timestamp":1554710369000},"page":"538-541","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cutaneous mantle cell lymphoma histomorphologically mimicking subcutaneous panniculitis\u2010like T\u2010cell lymphoma: Case report"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3819-9345","authenticated-orcid":false,"given":"Caroline","family":"Laggis","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Utah  Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney","family":"Miles","sequence":"additional","affiliation":[{"name":"Department of Pathology, Division of Clinical Pathology University of Utah  Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah M.","family":"Stephens","sequence":"additional","affiliation":[{"name":"Division of Hematology and Hematologic Malignancies, Department of Internal Medicine University of Utah  Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Duffy","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Utah  Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneli","family":"Bowen","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Utah  Salt Lake City 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