{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T12:17:23Z","timestamp":1767183443076,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T00:00:00Z","timestamp":1559001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 28\u2010year\u2010old woman of Chinese descent, with congenital chronic hepatitis B presented with a 7\u2010year history of erythematous\u2010brown papules and plaques on her groins, axillae, and forehead. A first skin biopsy showed findings consistent with two concomitant, yet highly uncommon cutaneous diseases. The presence of lymphoid nodules with germinal centers and clustered polyclonal plasma cells was consistent with cutaneous plasmocytosis. Second, a diffuse proliferation of non\u2010atypical small vessels (CD31+, CD34+, and HHV8\u2212) in a hypercellular stroma peppered with angulated giant cells (CD163+, CD68\u2212) was suggestive of multinucleate cell angiohistiocytoma (MCAH). Interestingly, the second biopsy of a different plaque on the forehead showed only plasmacytosis and the clinical appearance of both plaques and papules alluded to the distinct presence of both concurrent entities. We speculate the immune modulating effects of chronic hepatitis B may have led to a polyclonal plasmacytic proliferation within the dermis. Furthermore, MCAH has been reported in conjunction with other inflammatory skin diseases such as hidradenitis suppurativa and as such we propose that the MCAH lesion in our case may have arisen as a secondary, reactive process to the cutaneous plasmacytosis.<\/jats:p>","DOI":"10.1111\/cup.13491","type":"journal-article","created":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T16:52:07Z","timestamp":1557420727000},"page":"678-683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous plasmacytosis and multinucleate cell angiohistiocytoma\u2010like lesion in a patient with hepatitis B: A fortuitous triad?"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5444-0349","authenticated-orcid":false,"given":"Simon F.","family":"Roy","sequence":"first","affiliation":[{"name":"Division of Pathology University of Montr\u00e9al  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feras M.","family":"Ghazawi","sequence":"additional","affiliation":[{"name":"Division of Dermatology University of Ottawa  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Tran","sequence":"additional","affiliation":[{"name":"Dermatology Independent Practice  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Bouffard","sequence":"additional","affiliation":[{"name":"Division of Pathology University of Montr\u00e9al  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,28]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_4_2_1","DOI":"10.1097\/DAD.0000000000000907"},{"doi-asserted-by":"publisher","key":"e_1_2_4_3_1","DOI":"10.1097\/DAD.0000000000000075"},{"issue":"2","key":"e_1_2_4_4_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5070\/D30Z27T0XZ","article-title":"Multinucleate cell angiohistiocytoma: report of three new cases and literature review","volume":"15","author":"Jaconelli L","year":"2009","journal-title":"Dermatol Online J"},{"doi-asserted-by":"publisher","key":"e_1_2_4_5_1","DOI":"10.14218\/JCTH.2015.00024"},{"doi-asserted-by":"publisher","key":"e_1_2_4_6_1","DOI":"10.1016\/j.ijid.2010.12.008"},{"doi-asserted-by":"publisher","key":"e_1_2_4_7_1","DOI":"10.1038\/s41598-017-11975-7"},{"doi-asserted-by":"publisher","key":"e_1_2_4_8_1","DOI":"10.1016\/j.clml.2011.07.004"},{"doi-asserted-by":"publisher","key":"e_1_2_4_9_1","DOI":"10.1182\/blood.V97.6.1817"},{"doi-asserted-by":"publisher","key":"e_1_2_4_10_1","DOI":"10.1097\/DAD.0b013e3181baf070"},{"doi-asserted-by":"publisher","key":"e_1_2_4_11_1","DOI":"10.1111\/cup.13463"},{"doi-asserted-by":"publisher","key":"e_1_2_4_12_1","DOI":"10.1111\/cup.12268"},{"doi-asserted-by":"publisher","key":"e_1_2_4_13_1","DOI":"10.1034\/j.1600-0560.2002.290406.x"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13491","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13491","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13491","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T07:09:10Z","timestamp":1694329750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,28]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/cup.13491"],"URL":"https:\/\/doi.org\/10.1111\/cup.13491","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"type":"print","value":"0303-6987"},{"type":"electronic","value":"1600-0560"}],"subject":[],"published":{"date-parts":[[2019,5,28]]},"assertion":[{"value":"2019-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}