{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:46:08Z","timestamp":1783025168958,"version":"3.54.6"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T00:00:00Z","timestamp":1566432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cutaneous metastases from hepatocellular carcinoma (HCC) are extremely rare and can represent a sign of an underlying malignancy or relapse\/progression from an existing tumor. We report a case of a cutaneous metastasis arising in a patient with metastatic HCC following orthotopic liver transplantation. Diagnosis is a multistep process as cutaneous HCC metastases must be differentiated from primary cutaneous malignancies as well as other cutaneous metastases. Making this even more challenging, HCC metastases have heterogeneous clinical and histologic appearances. Therefore, the use of immunohistochemical stains, including hepatocyte paraffin\u20101, arginase\u20101, and glypican\u20103, and correlation with the clinical context are essential for a correct diagnosis.<\/jats:p>","DOI":"10.1111\/cup.13555","type":"journal-article","created":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T15:02:59Z","timestamp":1565017379000},"page":"47-51","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cutaneous metastasis of hepatocellular carcinoma following liver transplantation"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5665-102X","authenticated-orcid":false,"given":"Dawn","family":"Queen","sequence":"first","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliya","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Dermatology Columbia University Irving Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameera","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Pathology Columbia University Irving Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Linos","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Dartmouth\u2010Hitchcock Medical Center  Lebanon New Hampshire"},{"name":"Geisel School of Medicine at Dartmouth  Hanover New Hampshire"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George W.","family":"Niedt","sequence":"additional","affiliation":[{"name":"Department of Pathology Columbia University Irving Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faramarz H.","family":"Samie","sequence":"additional","affiliation":[{"name":"Department of Dermatology Columbia University Irving Medical Center  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,22]]},"reference":[{"issue":"4","key":"e_1_2_5_2_1","first-page":"339","article-title":"Multiple cutaneous metastases from hepatocellular carcinoma as the first sign of tumor recurrence in a transplant patient","volume":"103","author":"Alonso\u2010Gonz\u00e1lez J","year":"2012","journal-title":"Actas Dermosifiliogr"},{"key":"e_1_2_5_3_1","first-page":"838949","article-title":"Cutaneous metastases from primary hepatobiliary tumors as the first sign of tumor recurrence following liver transplantation","volume":"2014","author":"Hauch AT","year":"2014","journal-title":"Case Rep Transplant"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21706"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31823069cf"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/274357"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0051-RA"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1309\/8L872RPHEJRKF5JJ"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000377698"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pai.0000146525.72531.19"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2005.09.002"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200208000-00002"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0479-OA"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-7-149"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318158142f"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13555","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T10:39:13Z","timestamp":1694169553000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,22]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1111\/cup.13555"],"URL":"https:\/\/doi.org\/10.1111\/cup.13555","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,22]]},"assertion":[{"value":"2019-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}