{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T23:25:46Z","timestamp":1779924346386,"version":"3.53.1"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T00:00:00Z","timestamp":1580083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Perivascular epithelioid cell tumors (PEComas) are a group of lesions sharing the common features of co\u2010expression of melanocytic and myogenic markers, with focal association of the cells with vascular walls. The PEComa group exhibits a wide range of morphologies. A \u201cfibroma\u2010like\u201d variant of PEComa has been recently described. The case reported herein is that of an infant with tuberous sclerosis complex (TSC) presenting with a lip mass. Excisional biopsy showed a moderately cellular tumor composed of spindled to stellate cells embedded within a collagenized stroma. The cells showed focal perivascular accumulation and positivity for both melanocytic (HMB\u201045) and myogenic (desmin) markers. This is the fifth reported case of \u201cfibroma\u2010like\u201d PEComa in literature and the youngest patient to date. All of the \u201cfibroma\u2010like\u201d PEComas were found in patients with tuberous sclerosis\u2014hence, the diagnosis of this entity should prompt a workup for TSC; conversely, a fibroma\u2010like lesion in a patient with TSC or with TSC\u2010related conditions should be evaluated using melanocytic and myogenic markers. Melanocytic and myogenic markers are also useful in differentiating \u201cfibroma\u2010like\u201d PEComa from other differential diagnoses such as fibroma and benign fibrous histiocytoma.<\/jats:p>","DOI":"10.1111\/cup.13647","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T07:16:11Z","timestamp":1579072571000},"page":"548-553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cutaneous \u201cfibroma\u2010like\u201d perivascular epithelioid cell tumor: A case report and review of literature"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1766-7392","authenticated-orcid":false,"given":"Eugene I. G.","family":"Odo\u00f1o","sequence":"first","affiliation":[{"name":"Department of Pathology, College of Medicine University of the Philippines  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kong\u2010Bing","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Yong Loo Lin School of Medicine National University Health System and National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sok Yan","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Kwan Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Yong Loo Lin School of Medicine National University Health System and National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,27]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"230","volume-title":"WHO Classification of Tumours of Bone and Soft Tissue","author":"Hornick JL","year":"2013"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313029400169561"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199203000-00013"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.172"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2015.06.003"},{"issue":"2","key":"e_1_2_5_7_1","first-page":"1","article-title":"Tuberous sclerosis complex","volume":"26","author":"Henske EP","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024919"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1006242"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.52"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2289"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181f17ac0"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318161dc34"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001024"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-018-3065-7"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000173232.22117.37"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2009.09.002"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31824a8a37"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0075-RA"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13647","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13647","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T12:31:46Z","timestamp":1694003506000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,27]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/cup.13647"],"URL":"https:\/\/doi.org\/10.1111\/cup.13647","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,27]]},"assertion":[{"value":"2019-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}