{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T12:36:01Z","timestamp":1789043761466,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>SMARCA4\u2010deficient thoracic sarcoma (SMARCA4\u2010DTS) is a recently recognized entity with undifferentiated rhabdoid morphology and mutations in the switch\/sucrose nonfermenting BRG1\u2010associated factors complex. Patients are typically males in their fifth decade with a history of smoking who present with rapidly progressive intrathoracic disease and follow an aggressive clinical course. Metastatic disease is reported in up to 77% of cases; however, to our knowledge, cutaneous metastasis has not been reported nor has it been reported as the initial manifestation of the disease. Recognizing SMARCA4\u2010DTS from other types of epithelioid tumors that involve the skin is clinically relevant, as targeted therapies for SMARC\u2010deficient tumors are currently being investigated and early clinical trial data show therapeutic benefit.<\/jats:p>","DOI":"10.1111\/cup.13652","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T15:13:16Z","timestamp":1580310796000},"page":"561-565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Cutaneous metastasis of SMARCA4\u2010deficient thoracic sarcoma: A diagnostic dilemma with therapeutic implications"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8051-0657","authenticated-orcid":false,"suffix":"Jr.","given":"Bruce D.","family":"Leckey","sequence":"first","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology Duke University Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Angelica","family":"Selim","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology Duke University Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9431-0530","authenticated-orcid":false,"given":"Rami N.","family":"Al\u2010Rohil","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Pathology Duke University Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"issue":"1","key":"e_1_2_6_2_1","first-page":"66","article-title":"Cutaneous soft tissue tumors: diagnostically disorienting epithelioid tumors that are not epithelial, and other perplexing mesenchymal lesions","volume":"33","author":"Carter CS","year":"2019","journal-title":"Mod Pathol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3399"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.61"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.11"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001188"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0189-RA"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpdhp.2018.12.009"},{"issue":"2","key":"e_1_2_6_9_1","first-page":"237","article-title":"SMARCA4\u2010deficient thoracic sarcomatoid tumors represent primarily smoking\u2010related undifferentiated carcinomas rather than primary thoracic sarcomas","volume":"15","author":"Rekhtman N","year":"2019","journal-title":"J Thorac Oncol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001010"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1703966114"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30145-1"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.13652","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13652","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13652","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13652","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T12:31:26Z","timestamp":1694003486000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,13]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/cup.13652"],"URL":"https:\/\/doi.org\/10.1111\/cup.13652","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,13]]},"assertion":[{"value":"2019-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}