{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T07:25:24Z","timestamp":1769153124232,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Classic Ehlers\u2010Danlos syndrome (EDS) is a connective tissue disorder characterized by laxity. The skin, as one of the organs involved, shows hyperextensibility, which makes it prone to trauma. In this context, it would seem logical for cutaneous synovial metaplasia, which is considered a form of repair, to be commonly found in cases of EDS. However, there are only two previously published cases of synovial metaplasia in EDS. We present a third case in a 56\u2010year\u2010old woman with painful redundant skin in both elbows and knees for whom a skin fold of the left elbow was removed to relieve her symptoms. The biopsy showed preservation of the elastic and collagen fibers. The main alteration was the evidence of dermal cystic spaces lined by fibrinoid rests with focal pseudopapillary projections. However, in some zones the cellular lining was preserved, and it was composed of vimentin\u2010positive, fibroblast\u2010like flat, elongated cells, as well as CD68\u2010positive macrophages. No birefringent particles were found in an examination under polarized light.<\/jats:p>","DOI":"10.1111\/cup.13684","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T14:49:09Z","timestamp":1584197349000},"page":"729-733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cutaneous metaplastic synovial cyst in Ehlers\u2010Danlos syndrome"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6617-2364","authenticated-orcid":false,"given":"Angel","family":"Fernandez\u2010Flores","sequence":"first","affiliation":[{"name":"Department of Cellular Pathology Hospital Universitario El Bierzo  Ponferrada Spain"},{"name":"Department of Cellular Pathology Hospital de la Reina  Ponferrada Spain"},{"name":"Research Department, Institute for Biomedical Research of A Coru\u00f1a (INIBIC) University of A Coru\u00f1a (UDC)  A Coru\u00f1a Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan M.","family":"Barja\u2010Lopez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario El Bierzo  Ponferrada Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198705000-00002"},{"issue":"6","key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.5858\/2002-126-0727-SMASFO","article-title":"Synovial metaplasia, a specialized form of repair","volume":"126","author":"Fowler MR","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199708000-00016"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31815b9c82"},{"issue":"5","key":"e_1_2_5_6_1","first-page":"486","article-title":"Syndrome of 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