{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T17:09:39Z","timestamp":1775063379155,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary cutaneous B\u2010cell lymphomas are a heterogeneous group of lymphoid neoplasms primarily occurring in the skin. Although most cases are represented by primary cutaneous follicle center cell lymphoma, primary cutaneous marginal zone lymphoma and leg\u2010type diffuse large B\u2010cell lymphoma, other diffuse large B\u2010cell lymphomas and B\u2010cell lymphoblastic lymphoma may rarely present primarily in the skin. In this setting, the presence of histopathologic and immunohistochemical features of cellular immaturity is exceedingly rare and may represent a diagnostic challenge. We present the first case of a primary cutaneous diffuse large B\u2010cell lymphoma characterized by diminished expression of CD45, expression of TdT and rearrangement of <jats:italic>MYC<\/jats:italic> gene. The differential diagnosis mainly included B\u2010cell lymphoblastic lymphoma, and required the genetic analysis of heavy chain (IGH) gene rearrangements.<\/jats:p>","DOI":"10.1111\/cup.13795","type":"journal-article","created":{"date-parts":[[2020,7,5]],"date-time":"2020-07-05T04:25:50Z","timestamp":1593923150000},"page":"535-540","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["A case of primary cutaneous B\u2010cell lymphoma with immature features in an old man. Diffuse large B\u2010cell lymphoma with immature features or B\u2010cell lymphoblastic lymphoma?"],"prefix":"10.1111","volume":"48","author":[{"given":"Andrea","family":"Ronchi","sequence":"first","affiliation":[{"name":"Pathology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Zito Marino","sequence":"additional","affiliation":[{"name":"Pathology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Vitiello","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Caccavale","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Argenziano","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Crisci","sequence":"additional","affiliation":[{"name":"Hematology\u2010Oncology and Stem Cell Transplantation Unit, Istituto Nazionale Tumori, Fondazione \"G. Pascale\" IRCCS  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8340-3184","authenticated-orcid":false,"given":"Renato","family":"Franco","sequence":"additional","affiliation":[{"name":"Pathology Unit, Department of Mental and Physical Health and Preventive Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonello","family":"Sica","sequence":"additional","affiliation":[{"name":"Oncology and Hematology Unit, Department of Precision Medicine University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,9]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"300","volume-title":"Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerlow SH","year":"2017"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25224"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2016.1143939"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403202"},{"key":"e_1_2_4_6_1","unstructured":"U.S. National Library of Medicine. NCBI National Center for Biotechnology Information.https:\/\/www.ncbi.nlm.nih.gov\/igblast\/. Accessed January 3 2018."},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24436"},{"issue":"4","key":"e_1_2_4_8_1","first-page":"296","article-title":"Absence of occult HCV infection in patients experiencing an immunodepression condition","volume":"21","author":"Pisaturo M","year":"2013","journal-title":"Infez Med"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2018-0331"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2011.07.016"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-012-0305-y"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-017-0626-0"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.00954.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0702"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/00313020902756246"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200011000-00003"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1545"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31826cebad"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1515\/med-2020-0018"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000022"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e5060a"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2012.04301.x"},{"key":"e_1_2_4_23_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198805263182106"},{"key":"e_1_2_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2014.10.021"},{"key":"e_1_2_4_25_1","doi-asserted-by":"publisher","DOI":"10.1309\/NKK3FEX2BE5L7EKB"},{"key":"e_1_2_4_26_1","first-page":"6891957","article-title":"High\u2010grade B\u2010cell neoplasm with surface light chain restriction and TdT coexpression evolved in a MYC\u2010rearranged diffuse large b\u2010cell lymphoma: a dilemma in classification","volume":"2017","author":"Soliman DS","year":"2017","journal-title":"Case Rep Hematol"},{"key":"e_1_2_4_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000982"},{"key":"e_1_2_4_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402152"},{"key":"e_1_2_4_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2004.00338.x"},{"key":"e_1_2_4_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.142"},{"key":"e_1_2_4_31_1","doi-asserted-by":"publisher","DOI":"10.1309\/85CJ-U0X5-TE63-A8B3"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13795","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13795","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T15:05:09Z","timestamp":1693580709000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,9]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1111\/cup.13795"],"URL":"https:\/\/doi.org\/10.1111\/cup.13795","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,9]]},"assertion":[{"value":"2020-02-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}