{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:56:40Z","timestamp":1785783400787,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Spiradenocarcinoma (SC) is a very rare malignant skin adnexal tumor with sweat gland differentiation that develops from a pre\u2010existing spiradenoma, cylindroma, or hybrid tumor called spiradenocylindroma, or arises <jats:italic>de novo<\/jats:italic>. We present two exceptionally rare SC cases showing sarcomatous differentiation; we also discuss the clinicopathologic features of SC, as well as its differential diagnoses and available therapeutic modalities. Given the aggressive behavior of SC, rapid diagnosis and complete removal of the tumor with tumor\u2010free margins is mandatory. Owing to the marked morphological heterogeneity of individual SC cases, dermatopathologists must be familiar with the different possible histopathologic manifestations of this neoplasm.<\/jats:p>","DOI":"10.1111\/cup.13897","type":"journal-article","created":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T07:30:50Z","timestamp":1602660650000},"page":"384-389","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Metaplastic spiradenocarcinoma: Report of two cases with sarcomatous differentiation"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0836-2618","authenticated-orcid":false,"given":"Laura","family":"Held","sequence":"first","affiliation":[{"name":"Dermatopathology Friedrichshafen  Friedrichshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arno","family":"Ruetten","sequence":"additional","affiliation":[{"name":"Dermatopathology Friedrichshafen  Friedrichshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8814-441X","authenticated-orcid":false,"given":"Andrea","family":"Saggini","sequence":"additional","affiliation":[{"name":"Research Unit Dermatopathology, Department of Dermatology Medical University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Kempter","sequence":"additional","affiliation":[{"name":"Dermatopathology Friedrichshafen  Friedrichshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Tiedke","sequence":"additional","affiliation":[{"name":"Centre of Orthopedic and Trauma Surgery, Department of Oncologic Surgery, Sarcoma Centre Berlin  Brandenburg Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Weber\u2010Kuhn","sequence":"additional","affiliation":[{"name":"Pathology Department MVZ am Helios Klinikum Emil von Behring  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"De Saint Aubain","sequence":"additional","affiliation":[{"name":"Pathology Institut Jules, Bordet  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mentzel","sequence":"additional","affiliation":[{"name":"Dermatopathology Friedrichshafen  Friedrichshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.48"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10216"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09979-0"},{"issue":"2","key":"e_1_2_6_5_1","first-page":"388","article-title":"Malignant transformation of eccrine spiradenoma","volume":"11","author":"Dabska M","year":"1972","journal-title":"Pol Med J"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1997.tb00822.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23688.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000141548.69423.c7"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04460.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00608.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12136"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12448"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.5858\/2002-126-0591-MES"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181966762"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199712000-00003"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2004.03.007"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181a4f75c"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200004000-00002"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199008000-00002"},{"issue":"5","key":"e_1_2_6_20_1","first-page":"501","article-title":"Carcinosarcoma arising in eccrine spiradenoma of the breast. Report of a case and review of the literature","volume":"120","author":"Saboorian MH","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2005.00260.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000910"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2010.04.015"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13897","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13897","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T04:20:09Z","timestamp":1693714809000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,5]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/cup.13897"],"URL":"https:\/\/doi.org\/10.1111\/cup.13897","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,5]]},"assertion":[{"value":"2020-06-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}