{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:09:00Z","timestamp":1792696140013,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Drug\u2010induced psoriasiform alopecia is an increasingly recognized form of alopecia mostly reported in association with TNF\u2010alpha inhibitors. However, drug\u2010induced psoriasiform alopecia in association with IL\u201017A inhibitors has not been described. We present a 62\u2010year\u2010old woman with severe psoriasis who developed new psoriatic plaques on the scalp with alopecia after initiating ixekizumab (anti\u2010IL\u201017A). Scalp biopsy specimens revealed a non\u2010cicatricial alopecia with increased telogen\/catagen follicles, atrophy of the sebaceous glands, peribulbar and perifollicular inflammation with frequent lymphocytes, plasma cells, eosinophils, psoriasiform dermatitis, and lack of intra\u2010corneal or intra\u2010epidermal neutrophils. Overall, the clinical and histopathologic findings were most compatible with a drug\u2010induced psoriasiform alopecia in association with IL\u201017A inhibitor therapy. Our case shows that drug\u2010induced psoriasiform alopecia can paradoxically occur in patients on IL\u201017A inhibitor therapy and contributes to the growing list of cutaneous eruptions associated with biologic agents.<\/jats:p>","DOI":"10.1111\/cup.13952","type":"journal-article","created":{"date-parts":[[2021,1,3]],"date-time":"2021-01-03T03:48:36Z","timestamp":1609645716000},"page":"771-774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Drug\u2010induced psoriasiform alopecia associated with interleukin\u201017 inhibitor therapy"],"prefix":"10.1111","volume":"48","author":[{"given":"Timothy L.","family":"Tan","sequence":"first","affiliation":[{"name":"Consolidated Pathology Consultants  Libertyville Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Taglia","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northwestern Medicine Regional Medical Group  Naperville Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5648-4935","authenticated-orcid":false,"given":"Pedram","family":"Yazdan","sequence":"additional","affiliation":[{"name":"Division of Dermatopathology, Department of Dermatology Northwestern University Feinberg School of Medicine  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20061475"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2018.04.003"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/9781841847344"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181ef7403"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14695"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13375"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.2826"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13731"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14712598.2020.1727439"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13150"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2019.10.012"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000499030"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12932"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13227"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13952","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13952","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:59:30Z","timestamp":1693342770000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,12]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/cup.13952"],"URL":"https:\/\/doi.org\/10.1111\/cup.13952","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,12]]},"assertion":[{"value":"2020-06-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}