{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T05:27:39Z","timestamp":1773466059436,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,3,21]],"date-time":"2021-03-21T00:00:00Z","timestamp":1616284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>De\u2010differentiated chondrosarcoma (DDCS) is an extremely aggressive tumor of the bone characterized by a high\u2010grade, non\u2010chondroid sarcoma adjacent to a low\u2010 or intermediate\u2010grade chondrosarcoma. Adequate tumor sampling demonstrating the biphasic features is necessary to make an accurate diagnosis. The diagnosis may be challenging as histopathology may mimic other neoplasms. We present a case of a 76\u2010year\u2010old woman with a history of breast cancer who presented with a pathologic non\u2010displaced fracture. A bone biopsy demonstrated a high\u2010grade neoplasm composed of pleomorphic spindled and epithelioid cells with focal expression of AE1\/3 and GATA3, most likely consistent with metastatic breast carcinoma. After a difficult clinical course, the tumor was resected demonstrating a similar morphology to her prior biopsy, as well as an area of a low\u2010grade cartilaginous neoplasm consistent with chondrosarcoma. The biphasic tumor alongside a low\u2010grade chondrosarcoma allowed for a diagnosis of DDCS. Several days after her procedure, the patient developed violaceous nodules overlying and surrounding the surgical site. Skin biopsy demonstrated a malignant epithelioid neoplasm with identical histomorphologic features identical to her prior bone resection. Given the location of the skin lesions directly within the surgical site right after resection, the clinical\u2010pathological picture was that of sarcomatosis cutis by iatrogenic cutaneous implantation.<\/jats:p>","DOI":"10.1111\/cup.13995","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T04:59:55Z","timestamp":1614747595000},"page":"932-936","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<scp>GATA<\/scp>\u20103 expression in a de\u2010differentiated chondrosarcoma with cutaneous iatrogenic implantation: a diagnostic pitfall with important clinical implications"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1980-8515","authenticated-orcid":false,"given":"Ania","family":"Henning","sequence":"first","affiliation":[{"name":"Department of Pathology Summa Health System  Akron Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mackenzie","family":"Banks","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Medicine  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham M.","family":"Korman","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Internal Medicine The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. Hans","family":"Iwenofu","sequence":"additional","affiliation":[{"name":"Department of Pathology The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine G.","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Internal Medicine The Ohio State University  Columbus Ohio USA"},{"name":"Department of Pathology The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2018.05.009"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173665"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2017.04.019"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2015.05.018"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2016.11.004"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.06.016"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2017.05.015"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182a0218f"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000634"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000306"},{"key":"e_1_2_6_12_1","volume-title":"StatPearls","author":"Limaiem F","year":"2020"},{"key":"e_1_2_6_13_1","first-page":"317462","article-title":"UK guidelines for the management of bone sarcomas","volume":"2010","author":"Grimer R","year":"2010","journal-title":"Sarcoma"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30370"},{"issue":"3","key":"e_1_2_6_15_1","first-page":"73","article-title":"Cutaneous metastasis of chondrosarcoma: a case report with literature review","volume":"4","author":"Nazar E","year":"2019","journal-title":"CRCP"},{"issue":"6","key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1111\/ddg.13249","article-title":"Cutaneous sarcomas","volume":"15","author":"Kohlmeyer J","year":"2017","journal-title":"JDDG"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.5858\/2007-131-205-EAENOB"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0546-3"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13995","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.13995","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.13995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T04:39:19Z","timestamp":1693370359000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.13995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,21]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/cup.13995"],"URL":"https:\/\/doi.org\/10.1111\/cup.13995","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,21]]},"assertion":[{"value":"2020-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}