{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T21:00:56Z","timestamp":1760821256030,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T00:00:00Z","timestamp":1620518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cellular neurothekeoma is a cutaneous tumor with a distinctive histopathologic appearance characterized by a dermal\u2010based multinodular proliferation of epithelioid to spindled cells. Although the tumor may show varying amounts of myxoid stroma, extensive myxoid change is uncommon. The tumor typically presents as a solitary nodule with a predilection for the head and neck and upper limbs; examples of multiple cellular neurothekeomas are decidedly rare. The present report describes a unique case of multiple myxoid cellular neurothekeomas arising in a 60\u2010year\u2010old female with systemic lupus erythematosus. Two papular lesions were identified involving the skin inferior to the umbilicus and the left inguinal crease. Both lesions were histopathologically similar, forming a nodular mass composed of epithelioid cells in a prominent myxoid stroma. By immunohistochemistry the lesional cells expressed NKI\/C3, microphthalmia transcription factor (MiTF), and CD68, with focal staining for PGP9.5, factor XIIIa, and CD10 also observed. The tumors were negative for S\u2010100, SOX\u201010, epithelial membrane antigen, desmin, smooth muscle actin, glial fibrillary acid protein, and CD34. The present case confirms that cellular neurothekeoma can present clinically as multiple lesions and can have a predominantly myxoid appearance, potentially mimicking other cutaneous myxoid lesions.<\/jats:p>","DOI":"10.1111\/cup.14025","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T14:26:44Z","timestamp":1618237604000},"page":"980-985","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Multiple myxoid cellular neurothekeomas in a patient with systemic lupus erythematosus"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0805-0056","authenticated-orcid":false,"given":"Sean K.","family":"Lau","sequence":"first","affiliation":[{"name":"Southern California Permanente Medical Group, Department of Pathology Orange County\u2010Anaheim Medical Center  Anaheim California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8875-0858","authenticated-orcid":false,"given":"David S.","family":"Cassarino","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, Department of Pathology Los Angeles Medical Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen S.","family":"Koh","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, Department of Pathology Orange County\u2010Anaheim Medical Center  Anaheim California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213360.03133.89"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31802d96af"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.190"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2005.31623"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6987.2006.00400.x"},{"issue":"5","key":"e_1_2_6_7_1","first-page":"509","article-title":"Multiple desmoplastic cellular neurothekeomas localized to the face of a 16\u2010year\u2010old boy","volume":"32","author":"Garc\u00eda\u2010Guti\u00e9rrez M","year":"2010","journal-title":"Am J Dermatopathol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2010.01253.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2013.211"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.02.816"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-017-0828-8"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13366"},{"issue":"10","key":"e_1_2_6_13_1","first-page":"e126","article-title":"Neurothekeoma multiplicity\u2014a multiply occurring and recurrent case of a rare entity","volume":"41","author":"Myers DJ","year":"2019","journal-title":"Am J Dermatopathol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.13185"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199911000-00011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800043"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000173025.87476.a4"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199908000-00008"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1999.00633.x"},{"issue":"1","key":"e_1_2_6_20_1","first-page":"45","article-title":"Multiple dermatofibromas and systemic lupus erythematosus","volume":"37","author":"Lin RY","year":"1986","journal-title":"Cutis"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-010-0281-y"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155502320323171"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.203"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14025","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14025","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T04:39:11Z","timestamp":1693370351000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,9]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/cup.14025"],"URL":"https:\/\/doi.org\/10.1111\/cup.14025","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"type":"print","value":"0303-6987"},{"type":"electronic","value":"1600-0560"}],"subject":[],"published":{"date-parts":[[2021,5,9]]},"assertion":[{"value":"2021-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}