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Intravascular injection of foreign material is known to cause distal ischemia and necrosis due to thrombosis, local vasoconstriction, or microemboli formation. A 27\u2010year\u2010old male presented with retiform purpura and worsening distal fingertip necrosis of the right upper extremity accompanied by suspicious intravascular polarizable foreign material identified on skin, muscle, and vascular biopsies. We report a case that highlights concerning complications and dermatopathologic findings of intravascular injection of oral opioid tablets.<\/jats:p>","DOI":"10.1111\/cup.14039","type":"journal-article","created":{"date-parts":[[2021,5,2]],"date-time":"2021-05-02T10:33:41Z","timestamp":1619951621000},"page":"1173-1177","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous foreign body <scp>microemboli\u2010induced<\/scp> occlusive vasculopathy: A complication of illicit intravenous injection of oral opioid tablets"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6447-5254","authenticated-orcid":false,"given":"Marie","family":"Vu","sequence":"first","affiliation":[{"name":"University of Texas Health Science Center at San Antonio  San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Wisell","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Colorado  Denver Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendi","family":"Wohltmann","sequence":"additional","affiliation":[{"name":"Department of Dermatology Uniformed Services University of the Health Sciences, San Antonio Military Medical Center  San Antonio Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05607.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(78)90095-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.j.pain.0000460357.01998.f1"},{"key":"e_1_2_7_5_1","unstructured":"HardeyS ThomasS SteinS KelleyR AckermannK.What are the effects of shooting oxycodone?American Addiction Centers Website. 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