{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:58:22Z","timestamp":1791251902653,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Syringocystadenocarcinoma papilliferum (SCACP) is a rare cutaneous adnexal tumor thought to originate from its benign counterpart, syringocystadenoma papilliferum. These tumors are predominantly located on the head and neck with their location on the breast extraordinarily reported; mammary localization poses a great diagnostic dilemma to the practicing pathologist. Herein, we report an unusual case of an 85\u2010year\u2010old woman with an outside diagnosis on a core needle biopsy of metaplastic mammary carcinoma. Upon consultative review of the partial mastectomy specimen, SCACP was identified. Herein, we review SCACP and the diagnostic challenge it poses, especially when localized to the breast. Furthermore, we perform a retrospective review of institutional pathology reports and identified four additional cases of SCACP diagnosed at our institution within the last decade. Finally, we briefly review the literature of SCACP. The entity of SCACP should be well\u2009known to pathologists to avoid misdiagnosis.<\/jats:p>","DOI":"10.1111\/cup.14080","type":"journal-article","created":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T13:21:47Z","timestamp":1622899307000},"page":"1387-1391","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A rare case of syringocystadenocarcinoma papilliferum of the breast: An institutional retrospective case review and brief literature review"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2167-9054","authenticated-orcid":false,"given":"Jeffrey D.","family":"McBride","sequence":"first","affiliation":[{"name":"Department of Dermatopathology Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2278-5908","authenticated-orcid":false,"given":"Steven D.","family":"Billings","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miglena K.","family":"Komforti","sequence":"additional","affiliation":[{"name":"Department of Breast Pathology Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,16]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"9056209","article-title":"Metastatic syringocystadenocarcinoma papilliferum: a case report, tumor genomic profiling, and literature review","volume":"2020","author":"Altunel E","year":"2020","journal-title":"Case Rep Oncol Med"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1980.tb02939.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12934"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31826cffc6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3199019620"},{"key":"e_1_2_5_7_1","first-page":"638294","article-title":"Chemoradiotherapy in a case of malignant syringocystadenocarcinoma papilliferum of vulva with locoregional failure","volume":"2015","author":"Rao PB","year":"2015","journal-title":"Case Rep Oncol Med"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2017.03.021"},{"issue":"3","key":"e_1_2_5_9_1","first-page":"195","article-title":"Syringocystadenocarcinoma papilliferum: a rare malignant sweat gland tumor","volume":"16","author":"Yao JL","year":"2018","journal-title":"Skinmed"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13534"},{"key":"e_1_2_5_11_1","article-title":"Syringocystadenocarcinoma papilliferum with orbital invasion: a case report with literature review","volume":"11","author":"Pagano Boza C","year":"2019","journal-title":"Ther Adv Ophthalmol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181b96c0c"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.5858\/2009-0399-CR.1"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14080","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14080","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T02:36:03Z","timestamp":1693190163000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,16]]},"references-count":12,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/cup.14080"],"URL":"https:\/\/doi.org\/10.1111\/cup.14080","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,16]]},"assertion":[{"value":"2021-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}