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Angiocentricity is always associated with aggressive behavior or poor outcome in primary or secondary cutaneous lymphomas. Rare cases of angiocentric MF with a T\u2010cytotoxic immunophenotype (CD3+, CD4\u2212, CD8+, TIA\u20101+) have been described. Here, we report a 27\u2010year\u2010old man diagnosed with MF, clinically presenting with ichthyosiform lesions on his trunk and limbs. Biopsy demonstrated a CD3+ and CD8+ atypical lymphocytic infiltrate with marked epidermotropism and angiocentricity. Awareness of this rare MF variant with unusual clinicopathological characteristics is important to avoid misdiagnosis.<\/jats:p>","DOI":"10.1111\/cup.14188","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T07:05:38Z","timestamp":1639638338000},"page":"487-490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>CD8<\/scp>+ mycosis fungoides with ichthyosiform clinical presentation and angiocentric feature"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0213-7495","authenticated-orcid":false,"given":"Wei","family":"Ba","sequence":"first","affiliation":[{"name":"Department of Dermatology Chinese PLA General Hospital &amp; Medical School  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry (Hongyu)","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pathology St. Vincent Evansville Medical Center  Evansville Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chinese PLA General Hospital &amp; Medical School  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengxin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology Chinese PLA General Hospital &amp; Medical School  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2016.11.008"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60420-1"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-881268"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000759"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2016.04.006"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.00937.x"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2018.09.001"},{"issue":"2","key":"e_1_2_4_10_1","first-page":"73","article-title":"Variants of mycosis fungoides and related cutaneous T\u2010cell lymphomas","volume":"8","author":"LeBoit PE","year":"1991","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2019.01.004"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124696"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182648596"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31822067d1"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181fbb4fd"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.8.1052"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000355479"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2007.00778.x"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190802702383"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.07.043"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12371"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14188","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14188","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T10:14:57Z","timestamp":1692958497000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,28]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/cup.14188"],"URL":"https:\/\/doi.org\/10.1111\/cup.14188","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,28]]},"assertion":[{"value":"2021-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}