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We describe a 33\u2010year\u2010old man who presented with progressive facial swelling and lower lip involvement 1\u2009year ago. Microscopy revealed an atypical small to medium\u2010sized lymphoid proliferation exhibiting perivascular accentuation, adnexotropism, and apoptotic cell debris, without surface epithelium involvement. The tumor cells were positive for CD3, CD8, granzyme B, perforin, MUM1\/IRF4, and TCR\u2010BF1. The Ki\u201067 labeling index was 48%. EBER1\/2 was negative. Additional studies confirmed localized disease. The diagnosis favored PC\u2010PTCL\u2010NOS. Two months after completing chemotherapy, right\u2010sided facial nerve palsy was diagnosed. CD8+ T\u2010cell LPDs should be considered in the differential diagnosis when assessing facial swelling with intraoral involvement.<\/jats:p>","DOI":"10.1111\/cup.14199","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T06:29:50Z","timestamp":1641796190000},"page":"560-564","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Primary cutaneous <scp>CD8<\/scp>+ cytotoxic T\u2010cell lymphoma of the face with intraoral involvement, resulting in facial nerve palsy after chemotherapy"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4286-0714","authenticated-orcid":false,"given":"Daphine Caxias","family":"Travassos","sequence":"first","affiliation":[{"name":"Oral Medicine, Department of Diagnosis and Surgery, Araraquara Dental School S\u00e3o Paulo State University (UNESP)  Araraquara 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