{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:56:59Z","timestamp":1747184219525,"version":"3.40.5"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dystrophic calcification is a common histopathologic finding that can be concomitant with a plethora of diseases, ranging from self\u2010limited infections to insidious malignancies. Gamna\u2010Gandy bodies (GGBs) are a form of dystrophic calcification associated with chronic hemolysis and are typically observed in the spleen. In this report, we present the case of a 92\u2010year\u2010old man who presented with a 4\u2010mm blue papule that was biopsied given the concern for a blue nevus. The subsequent histopathologic examination of the biopsy specimen showed a dermal organizing hematoma adjacent to pale\u2010yellow to brown, refractile material within fibrotic collagen consistent with GGBs. Scanning electron microscopy with energy\u2010dispersive x\u2010ray analysis (SEM\/EDXA) revealed that the structures were composed of carbon (39%), oxygen (32%), iron (16%), phosphorus (7%), calcium (5%), and sodium (1%). Fourier transform infrared spectroscopy identified amorphous calcium phosphate. GGBs have not been previously described in the skin and have been rarely characterized with SEM\/EDXA in other sites.<\/jats:p>","DOI":"10.1111\/cup.14202","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T14:06:02Z","timestamp":1641996362000},"page":"570-574","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cutaneous <scp>Gamna\u2010Gandy<\/scp> bodies: An unusual case of dystrophic calcification"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8436-990X","authenticated-orcid":false,"given":"Jeffrey A.","family":"Sanford","sequence":"first","affiliation":[{"name":"Department of Pathology Walter Reed National Military Medical Center  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacy L.","family":"Strausborger","sequence":"additional","affiliation":[{"name":"Environmental Pathology Joint Pathology Center  Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Lewin\u2010Smith","sequence":"additional","affiliation":[{"name":"Environmental Pathology Joint Pathology Center  Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Royer","sequence":"additional","affiliation":[{"name":"Dermatopathology Joint Pathology Center  Silver Spring Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2013.06.003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2841"},{"issue":"4","key":"e_1_2_7_4_1","first-page":"475","article-title":"Wound fragments from cutaneous sites of U.S. military personnel deployed in Operation Iraqi Freedom: clinical aspects and pathologic characterizations","volume":"34","author":"Maggio KL","year":"2008","journal-title":"Dermatol Surg"},{"key":"e_1_2_7_5_1","first-page":"65","volume-title":"Tumors of the Thyroid Gland, Atlas of Tumor Pathology","author":"Rosai J","year":"1992"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896916645185"},{"issue":"11","key":"e_1_2_7_7_1","first-page":"1166","article-title":"Pseudofungi in a lymph node. A case report with energy dispersive X\u2010ray elemental analysis","volume":"115","author":"Connelly J","year":"1991","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.5858\/2005-129-e97-PIPLN"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/63.2.106"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4322\/acr.2018.076"},{"key":"e_1_2_7_11_1","first-page":"1","article-title":"Gamna\u2010Gandy bodies in pediatric thyroid nodular hyperplasia","volume":"20","author":"Cano C","year":"2020","journal-title":"Hum Pathol Case Rep"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/2277-8632.185458"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijc.IJC_170_18"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5858\/2003-127-0372-GGNIAR"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23714"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(01)00451-9"},{"issue":"8","key":"e_1_2_7_17_1","first-page":"744","article-title":"Elastin fibers resembling Sporothrix schenkii in the skin of a patient with acquired immunodeficiency syndrome","volume":"119","author":"Skrade JJ","year":"1995","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2011.08.011"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14202","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T17:09:36Z","timestamp":1692983376000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,24]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/cup.14202"],"URL":"https:\/\/doi.org\/10.1111\/cup.14202","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"type":"print","value":"0303-6987"},{"type":"electronic","value":"1600-0560"}],"subject":[],"published":{"date-parts":[[2022,1,24]]},"assertion":[{"value":"2021-10-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}