{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:43Z","timestamp":1787014063866,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,2,20]],"date-time":"2022-02-20T00:00:00Z","timestamp":1645315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Histopathologic differentiation of lichen planopilaris (LPP) and discoid lupus erythematosus (DLE) as two common causes of primary cicatricial alopecias remains challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We performed a histopathologic study on a case series of LPP and DLE specimens to investigate the number, distribution, and morphology of mast cells as indices for differentiation of these two entities. H&amp;E investigation and Giemsa staining for the detection of mast cells was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      A total of 74 cases comprising 50 cases of LPP and 24 cases of DLE were assessed. The mean mast cell count and percentage were significantly higher in LPP group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Mean degranulated mast cell count and the mean intact mast cell count were also significantly higher in LPP patients (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Most of the specimens, 58 (78.4%), showed both perifollicular and perivascular distribution of mast cells without significant difference between two groups. The morphology of mast cells was predominantly round\u2010oval in 85.5%, predominantly fusiform in 13.5% with more frequent fusiform morphology in DLE group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The mast cell count detected by Giemsa staining could assist pathologists in distinguishing between LPP and DLE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cup.14207","type":"journal-article","created":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T08:00:08Z","timestamp":1643702408000},"page":"448-453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The presence of mast cells in lichen planopilaris and discoid lupus erythematosus of the scalp: A quantitative study"],"prefix":"10.1111","volume":"49","author":[{"given":"Mohammad","family":"Shahidi\u2010Dadras","sequence":"first","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Asadi Kani","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4058-2562","authenticated-orcid":false,"given":"Sahar","family":"Dadkhahfar","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Zartab","sequence":"additional","affiliation":[{"name":"Center for Research &amp; Training in Skin Diseases &amp; Leprosy Tehran University of Medical Sciences  Tehran Iran"},{"name":"Department of Dermatology Afzalipour Hospital, Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2208-4244","authenticated-orcid":false,"given":"Azadeh","family":"Rakhshan","sequence":"additional","affiliation":[{"name":"Skin Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"},{"name":"Department of Pathology, Shohada\u2010e\u2010Tajrish Educational Hospital, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.09.058"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.056"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.130409"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2014.06.016"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.83.164"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-015-1539-1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijt.ijt_43_16"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02114.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2015.03.021"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1964.152"},{"key":"e_1_2_6_12_1","first-page":"8","article-title":"Mast cells in non\u2010neoplastic skin lesions","volume":"145","author":"Joshi MM","year":"2013","journal-title":"Indian Med Gaz"},{"issue":"2","key":"e_1_2_6_13_1","first-page":"759630","article-title":"A comparative analysis of mast cell quantification in five common dermatoses: lichen simplex chronicus, psoriasis, lichen planus, lupus, and insect bite\/allergic contact dermatitis\/nummular dermatitis","volume":"2012","author":"Patel N","year":"2012","journal-title":"Int Scholarly Res Notices"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13816"},{"key":"e_1_2_6_15_1","unstructured":"HarriesM.The Immunopathobiology of Lichen Planopilaris[Thesis]. 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