{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:33:48Z","timestamp":1758710028492,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T00:00:00Z","timestamp":1650240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>During the 2020 coronavirus (SARS\u2010CoV\u20102) pandemic, several cutaneous lesions were identified, including pseudo\u2010chilblain, vesicular, urticarial, maculopapular, and livedo\/necrosis. A 59\u2010year\u2010old obese man with probable COVID\u201019 developed painful cyanosis with histopathologic capillary thrombosis of toes, and the cyanosis persisted for nearly 22\u2009months. Shortly after initial exposure to family members with documented SARS\u2010CoV\u20102, he developed upper respiratory symptoms, yet his anti\u2010SARS\u2010CoV\u20102 antibody and nasal swab RT\u2010PCR tests were repeatedly negative. Two family members were hospitalized and one of them succumbed with documented SARS\u2010CoV\u20102 pneumonia within 10\u2009days of exposure. Biopsy specimen of the distal toe 16\u2009weeks after initial exposure showed papillary dermal capillary thrombosis with endothelial swelling, telangiectasia, and peri\u2010eccrine lymphocytic infiltrates resembling pernio. Overall, this is the first case of biopsy specimen of \u201clong COVID toe\u201d following presumed SARS\u2010CoV\u20102 exposure, with a demonstration of thrombotic vasculopathy, toe cyanosis, and pernio\u2010like pathology.<\/jats:p>","DOI":"10.1111\/cup.14240","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T12:19:06Z","timestamp":1648901946000},"page":"791-794","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Histopathology of persistent long <scp>COVID<\/scp> toe: A case report"],"prefix":"10.1111","volume":"49","author":[{"given":"Michael S.","family":"Nirenberg","sequence":"first","affiliation":[{"name":"Friendly Foot Care, P.C.  Crown Point Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1347-3507","authenticated-orcid":false,"given":"Luis","family":"Requena","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Santonja","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1502-3913","authenticated-orcid":false,"given":"Gregory T.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pharmacological Sciences Stony Brook University  Stony Brook New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve A.","family":"McClain","sequence":"additional","affiliation":[{"name":"Department of Dermatology Stony Brook University  Stony Brook New York USA"},{"name":"Department of Emergency Medicine Stony Brook University  Stony Brook New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19163"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13986"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000001829"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/dermatopathology7010002"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13866"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14099"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(20)30986\u20105"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/00033197211068938"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20\u20101495"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(20)30518\u20101"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2020.07.009"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14240","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14240","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14240","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T10:47:45Z","timestamp":1692787665000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,18]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/cup.14240"],"URL":"https:\/\/doi.org\/10.1111\/cup.14240","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"type":"print","value":"0303-6987"},{"type":"electronic","value":"1600-0560"}],"subject":[],"published":{"date-parts":[[2022,4,18]]},"assertion":[{"value":"2021-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}