{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:15:09Z","timestamp":1778796909956,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,7]],"date-time":"2022-08-07T00:00:00Z","timestamp":1659830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Clonal B\u2010cell proliferations and B\u2010cell lymphomas may co\u2010occur in the background of follicular helper T\u2010cell (TFH)\u2010derived lymphomas, most associated with EBV, which has been a well\u2010known fact for many years in the prototypical entity \u201cTFH lymphoma, angioimmunoblastic\u2010type.\u201d Primary cutaneous CD4+ small\/medium T\u2010cell\u00a0lymphoproliferative disorder (CD4<jats:sup>+<\/jats:sup> PCSM\u2010LPD) is also a TFH\u2010derived clonal proliferation. We searched the archives and identified four cases of CD4<jats:sup>+<\/jats:sup> PCSM\u2010LPD with accompanying clonal B\u2010cell proliferation (one of which showed EBER positivity), and one longstanding case of CD4<jats:sup>+<\/jats:sup> PCSM\u2010LPD, in the background of which a B\u2010cell lymphoma had developed. These five cases broaden experience on CD4<jats:sup>+<\/jats:sup> PCSM\u2010LPD with accompanying B\u2010cell proliferations and also support routine evaluation of these cases with EBV in situ hybridization, to better determine whether or not there is an association with EBV.<\/jats:p>","DOI":"10.1111\/cup.14296","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T03:03:28Z","timestamp":1658718208000},"page":"971-977","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clonal B\u2010cell proliferations developing in the background of primary cutaneous CD4<sup>+<\/sup> small\/medium T\u2010cell lymphoproliferative disorder: A case series"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9051-0343","authenticated-orcid":false,"given":"Deniz","family":"Ates Ozdemir","sequence":"first","affiliation":[{"name":"Department of Pathology Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1137-5399","authenticated-orcid":false,"given":"Neslihan","family":"Akdo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5317-0597","authenticated-orcid":false,"given":"M\u00fcfide","family":"Okay","sequence":"additional","affiliation":[{"name":"Department of Hematology Ministry of Health, Eski\u015fehir City Hospital  Eski\u015fehir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2522-1606","authenticated-orcid":false,"given":"Ayseg\u00fcl","family":"Uner","sequence":"additional","affiliation":[{"name":"Department of Pathology Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0076-8293","authenticated-orcid":false,"given":"Arzu","family":"Saglam","sequence":"additional","affiliation":[{"name":"Department of Pathology Hacettepe University  Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,7]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"401","volume-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Gaulard 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