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We report a rare case of non\u2010invasive colorectal\u2010adenoma\u2010associated PPD. In this case, the intraepithelial Paget cells of perianal skin manifested with colorectal phenotype by immunohistochemistry, and adjacent adenomas had high\u2010grade intraepithelial neoplasia but not invasion. Although this is a rare manifestation of PPD, understanding this phenomenon is important to prevent overdiagnosis and invasive overtreatment. Clinical management is variable and, therefore, close follow\u2010up examination is necessary.<\/jats:p>","DOI":"10.1111\/cup.14314","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T16:18:54Z","timestamp":1660839534000},"page":"35-38","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Perianal Paget disease associated with non\u2010invasive colorectal adenoma"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3222-4530","authenticated-orcid":false,"given":"Zhibo","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Pathology First Hospital of Jiaxing  Jiaxing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanxin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pathology First Hospital of Jiaxing  Jiaxing 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