{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:41:36Z","timestamp":1792597296074,"version":"4.5.0"},"reference-count":63,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Melanoma of the nail apparatus is challenging to diagnose for both dermatologists and dermatopathologists. Misdiagnosis or delayed diagnosis of nail unit melanoma can have fatal consequences and legal ramifications. This review educates dermatopathologists on challenges and traps they should be aware of to avoid misdiagnosis of nail unit melanoma. We present illustrative difficult cases that introduce several themes regarding challenges in the diagnosis of nail unit melanoma: specimens with subtle histopathologic findings, challenges in immunoperoxidase interpretation, and how clinical knowledge and surgical procedural knowledge are mandatory to make the diagnosis. Dermatopathologists will be aware of when and how to suspect nail unit melanoma in unusual circumstances.<\/jats:p>","DOI":"10.1111\/cup.14403","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T15:44:30Z","timestamp":1675784670000},"page":"580-590","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Clinicohistopathologic challenges and traps in the diagnosis of nail unit melanoma"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9845-6238","authenticated-orcid":false,"given":"Angela J.","family":"Jiang","sequence":"first","affiliation":[{"name":"Summit Health  Woodland Park New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0952-4148","authenticated-orcid":false,"given":"James J.","family":"Abbott","sequence":"additional","affiliation":[{"name":"Billings Clinic  Billings Montana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. William","family":"Higgins","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalie","family":"Elenitsas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9273-1817","authenticated-orcid":false,"given":"Adam I.","family":"Rubin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2006.03.012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2021.33.2.147"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.1372"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365\u201005962013000200029"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16762"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.5070\/D35bt0c996"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.2012.04418.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13418"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13529"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.1894"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14715"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102133.1998.02365.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318073c600"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.04.044"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2008.609"},{"issue":"1","key":"e_1_2_7_17_1","first-page":"82","article-title":"The spectrum of malignant melanoma of the nail apparatus","volume":"10","author":"Dawber RP","year":"1991","journal-title":"Semin Dermatol"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2006.07368.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3243038614"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.2307"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.43"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17036"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.14027"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346\u20108138.15158"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13333"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000001480"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000001474"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12558"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12197"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2021.05.007"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0146"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000003233"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000003317"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182545ccd"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adengl.2013.06.001"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0143"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2020.12.009"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31815c8578"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0190\u20109622(94)70144\u2010x"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372\u2010199710000\u201000005"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2015.27.3.328"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.010"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181e67c87"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0190\u20109622(96)90010\u20109"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2016.08.005"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000940"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14925"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31826b74b8"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12634"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.038"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2013.06.005"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.5869"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12976"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488722"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13457"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000002156"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14226"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14201"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.13007"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14377"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14150"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.03.030"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896916648379"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14279"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cup.14403","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.14403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T16:46:02Z","timestamp":1692549962000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.14403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,24]]},"references-count":63,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/cup.14403"],"URL":"https:\/\/doi.org\/10.1111\/cup.14403","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,24]]},"assertion":[{"value":"2022-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}