{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:57:04Z","timestamp":1791309424938,"version":"4.3.1"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T00:00:00Z","timestamp":1678233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Microsecretory adenocarcinoma (MSA) is a newly described salivary gland tumor harboring a characteristic balanced chromosomal translocation resulting in <jats:italic>MEF2C::SS18<\/jats:italic> gene fusion. Six primary cutaneous MSA cases have been recently described. We report three additional cases confirming the relevance of this recently identified entity of primary cutaneous adnexal tumor. Three patients aged 53\u2010, 64\u2010 and 78\u2010year\u2010old were retrospectively diagnosed with MSA of the skin (MSAS) as consultation cases of the CARADERM (CAncers RAres DERMatologiques) national network. The clinical presentation was an indolent nodule on the upper extremities. There was no history of salivary gland tumor. Histopathologically, the tumors presented as dermal nodular proliferation with slightly infiltrative borders, composed of cribriform and microcystic structures with abundant myxoid intraluminal secretion embedded in a fibromyxoid stroma. They diffusely expressed cytokeratin 8 and SOX10, focally p63 and heterogeneously smooth muscle actin. All tumors harbored the <jats:italic>MEF2C::SS18<\/jats:italic> gene fusion. A complete surgical excision was performed. No local recurrence or distant metastases were observed so far (follow\u2010up: 17, 38, and 45\u2009months). MSAS is the cutaneous homologue of MSA of the salivary gland, a low\u2010grade adnexal neoplasm whose prognosis seems to be excellent once the complete removal of the tumor is assured.<\/jats:p>","DOI":"10.1111\/cup.14408","type":"journal-article","created":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T11:57:05Z","timestamp":1676462225000},"page":"897-902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Microsecretory adenocarcinoma of the skin, a novel type of sweat gland carcinoma: Report of three additional cases"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4494-6124","authenticated-orcid":false,"given":"Sofia","family":"Bogiatzi","sequence":"first","affiliation":[{"name":"Pathology Department Saint\u2010Louis Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Estenaga","sequence":"additional","affiliation":[{"name":"Pathology Department Saint\u2010Louis Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baptiste","family":"Louveau","sequence":"additional","affiliation":[{"name":"Solid Tumor Genomics Department Saint\u2010Louis Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Osio","sequence":"additional","affiliation":[{"name":"Pathology Department Saint\u2010Louis Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Deschamps","sequence":"additional","affiliation":[{"name":"Pathology Department Bichat Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"Mourah","sequence":"additional","affiliation":[{"name":"Solid Tumor Genomics Department Saint\u2010Louis Hospital  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9  Paris France"},{"name":"INSERM U976  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Poirot","sequence":"additional","affiliation":[{"name":"Solid Tumor Genomics Department Saint\u2010Louis Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Lehmann\u2010Che","sequence":"additional","affiliation":[{"name":"Solid Tumor Genomics Department Saint\u2010Louis Hospital  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9  Paris France"},{"name":"INSERM U976  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Cribier","sequence":"additional","affiliation":[{"name":"Dermatopathology Unit, Clinique Dermatologique H\u00f4pitaux Universitaires de Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Battistella","sequence":"additional","affiliation":[{"name":"Pathology Department Saint\u2010Louis Hospital  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9  Paris France"},{"name":"INSERM U976  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,8]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"154","volume-title":"WHO Classification of Tumours","author":"Massi D","year":"2018"},{"key":"e_1_2_6_3_1","first-page":"171","volume-title":"WHO Classification of Head and Neck Tumours","author":"Leivo I","year":"2017"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000980"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000734"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001273"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105\u2010021\u201001331\u20107"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105\u2010022\u201001422\u2010z"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14271"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14277"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000002270"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2021.11.027"},{"key":"e_1_2_6_13_1","unstructured":"GeneCards.The Human Gene Database. 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